John S Tregoning
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Explore the profile of John S Tregoning including associated specialties, affiliations and a list of published articles.
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94
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3506
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Recent Articles
1.
Peeler D, Sun R, Kutahya C, Peschke P, Zhou K, Brachi G, et al.
Adv Mater
. 2025 Feb;
:e2417290.
PMID: 40018867
Two-photon polymerization (2PP) 3D printing enables top-down biomaterial synthesis with nanoscale spatial resolution for de novo design of monodisperse injectable drug delivery systems. Spatiotemporal Controlled Release Inks of Biocompatible polyEsters...
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3.
Stirling D, de Miguel Ferrer M, Kim S, Wane M, Kysh D, Caproni L, et al.
Hum Vaccin Immunother
. 2025 Jan;
21(1):2430826.
PMID: 39829233
The COVID-19 pandemic highlighted the need for rapidly deployable, flexible vaccine platforms; particularly RNA which is now being explored for several other pathogens. DNA vaccines have potential advantages over RNA,...
4.
Barton R, Tregoning J, Wang Z, Goncalves-Carneiro D, Patel R, McKay P, et al.
Mol Ther Nucleic Acids
. 2025 Jan;
36(1):102400.
PMID: 39759876
Self-amplifying RNA (saRNA) is an extremely promising platform because it can produce more protein for less RNA. We used a sort and sequence approach to identify host cell factors associated...
5.
Wang Z, Zhong M, Thomas C, Kinnear E, Rice T, Holder B, et al.
Npj Viruses
. 2025 Jan;
2(1):71.
PMID: 39749186
Maternal immunisation against respiratory viruses provides protection in early life, but as antibodies wane, there can be a gap in coverage. This immunity gap might be filled by inducing pathogen-specific...
6.
Fenn J, Madon K, Conibear E, Derelle R, Nevin S, Kundu R, et al.
EBioMedicine
. 2024 Dec;
111():105475.
PMID: 39667271
Background: A proportion of individuals exposed to respiratory viruses avoid contracting detectable infection. We tested the hypothesis that early innate immune responses associate with resistance to detectable infection in close...
7.
Chen K, Najer A, Charchar P, Saunders C, Thanapongpibul C, Klockner A, et al.
Nat Commun
. 2024 Nov;
15(1):10321.
PMID: 39609415
Staphylococcus aureus is a leading cause of nosocomial implant-associated infections, causing significant morbidity and mortality, underscoring the need for rapid, non-invasive, and cost-effective diagnostics. Here, we optimise the synthesis of...
8.
Waldock J, Cox R, Chiu C, Subbarao K, Wildfire A, Barclay W, et al.
Influenza Other Respir Viruses
. 2024 Nov;
18(11):e70014.
PMID: 39496425
Controlled human infection models (CHIMs) are a critical tool for the understanding of infectious disease progression, characterising immune responses to infection and rapid assessment of vaccines or drug treatments. There...
9.
Waldock J, Cox R, Engelhardt O, Ascough S, Osterhaus A, Rimmelzwaan G, et al.
Influenza Other Respir Viruses
. 2024 Oct;
18(10):e70013.
PMID: 39440808
Controlled human infection models (CHIMs) are a critical tool for the understanding of infectious disease progression, characterising immune responses to infection and rapid assessment of vaccines or drug treatments. There...
10.
Clark T, Tregoning J, Lister H, Poletti T, Amin F, Nguyen-Van-Tam J
Clin Microbiol Rev
. 2024 Oct;
37(4):e0002524.
PMID: 39360831
SUMMARYIn the United Kingdom (UK) in 2022/23, influenza virus infections returned to the levels recorded before the COVID-19 pandemic, exerting a substantial burden on an already stretched National Health Service...