John S Tregoning
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Explore the profile of John S Tregoning including associated specialties, affiliations and a list of published articles.
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94
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3506
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Recent Articles
11.
Murugaiah V, Murugaiah V, Watson S, Watson S, Cunliffe R, Cunliffe R, et al.
J Infect Dis
. 2024 Sep;
231(2):e299-e307.
PMID: 39317662
The development of a universal influenza vaccine likely requires an understanding of previous exposure to influenza virus (through vaccination or infection) and how that shapes the antibody repertoire to vaccination,...
12.
Baker S, Krishna A, Higham S, Naydenova P, OLeary S, Scott J, et al.
Nat Commun
. 2024 Sep;
15(1):7979.
PMID: 39266557
The use of monoclonal antibodies for the control of drug resistant nosocomial bacteria may alleviate a reliance on broad spectrum antimicrobials for treatment of infection. We identify monoclonal antibodies that...
13.
Barbieri B, Peeler D, Samnuan K, Day S, Hu K, Sallah H, et al.
J Control Release
. 2024 Aug;
374:280-292.
PMID: 39142355
Lipid nanoparticle (LNP) formulation plays a vital role in RNA vaccine delivery. However, further optimisation of self-amplifying RNA (saRNA) vaccine formulation could help enhance seroconversion rates in humans and improve...
14.
Owen A, Farias A, Levins A, Wang Z, Higham S, Mack M, et al.
Mucosal Immunol
. 2024 Aug;
17(6):1184-1198.
PMID: 39127259
Respiratory syncytial virus (RSV) can cause severe lower respiratory tract infections. Understanding why some individuals get more serious disease may help with diagnosis and treatment. One possible risk factor underlying...
15.
16.
Bissett C, Belij-Rammerstorfer S, Ulaszewska M, Smith H, Kailath R, Morris S, et al.
NPJ Vaccines
. 2024 Jun;
9(1):118.
PMID: 38926455
Although licensed vaccines against influenza virus have been successful in reducing pathogen-mediated disease, they have been less effective at preventing viral infection of the airways and current seasonal updates to...
17.
Styles C, Zhou J, Flight K, Brown J, Lewis C, Wang X, et al.
EMBO Mol Med
. 2024 Jun;
16(7):1751.
PMID: 38844556
No abstract available.
18.
Cunliffe R, Stirling D, Razzano I, Murugaiah V, Montomoli E, Kim S, et al.
Discov Immunol
. 2024 Apr;
3(1):kyad030.
PMID: 38567290
Influenza virus represents a challenge for traditional vaccine approaches due to its seasonal changes and potential for zoonotic transmission. Nucleic acid vaccines can overcome some of these challenges, especially through...
19.
Talts T, Mosscrop L, Williams D, Tregoning J, Paulo W, Kohli A, et al.
Microbiol Spectr
. 2024 Feb;
12(4):e0306723.
PMID: 38411056
Importance: In this paper, we report an improved high-throughput respiratory syncytial virus (RSV) whole-genome sequencing (WGS) assay performed directly on clinical samples, using a 4-primer-pool, short-amplicon PCR-tiling approach that is...
20.
Wang Z, Cuthbertson L, Thomas C, Sallah H, Mosscrop L, Li H, et al.
Mucosal Immunol
. 2024 Feb;
17(2):272-287.
PMID: 38382577
Respiratory viral infections remain a major cause of hospitalization and death worldwide. Patients with respiratory infections often lose weight. While acute weight loss is speculated to be a tolerance mechanism...