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John Paul Oliveria

Explore the profile of John Paul Oliveria including associated specialties, affiliations and a list of published articles. Areas
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Citations 395
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Recent Articles
1.
Ju X, Fard N, Bhalla A, Dvorkin-Gheva A, Xiao M, Radford K, et al.
Sci Transl Med . 2025 Jan; 17(781):eado6649. PMID: 39813318
In prednisone-dependent severe asthma, uncontrolled sputum eosinophilia is associated with increased numbers of group 2 innate lymphoid cells (ILC2s). These cells represent a relatively steroid-insensitive source of interleukin-5 (IL-5) and...
2.
Bauer R, Xie Y, Beaudin S, Wiltshire L, Wattie J, Munoz C, et al.
Clin Exp Allergy . 2023 Oct; 53(11):1187-1197. PMID: 37794659
Background: Similar immune responses in the nasal and bronchial mucosa implies that nasal allergen challenge (NAC) is a suitable early phase experimental model for drug development targeting allergic rhinitis (AR)...
3.
Mrdjen D, Amouzgar M, Cannon B, Liu C, Spence A, McCaffrey E, et al.
Res Sq . 2023 Jul; PMID: 37398389
Microglia are implicated in aging, neurodegeneration, and Alzheimer's disease (AD). Traditional, low-plex, imaging methods fall short of capturing cellular states and interactions in the human brain. We utilized Multiplexed Ion...
4.
Jiang S, Chan C, Rovira-Clave X, Chen H, Bai Y, Zhu B, et al.
Immunity . 2022 Apr; 55(6):1118-1134.e8. PMID: 35447093
Understanding the mechanisms of HIV tissue persistence necessitates the ability to visualize tissue microenvironments where infected cells reside; however, technological barriers limit our ability to dissect the cellular components of...
5.
Xie Y, Ju X, Beaudin S, Wiltshire L, Oliveria J, MacLean J, et al.
Allergy . 2021 Mar; 76(9):2797-2808. PMID: 33784411
Background: Allergic rhinitis is characterized by rhinorrhea, nasal congestion, sneezing and nasal pruritus. Group 2 innate lymphoid cells (ILC2s), CD4 T cells and eosinophils in nasal mucosa are increased significantly...
6.
Oliveria J, Agayby R, Gauvreau G
Methods Mol Biol . 2021 Jan; 2270:375-418. PMID: 33479910
Allergic asthma is triggered by inhalation of environmental allergens resulting in bronchial constriction and inflammation, which leads to clinical symptoms such as wheezing, coughing, and difficulty breathing. Asthmatic airway inflammation...
7.
Glass D, Tsai A, Oliveria J, Hartmann F, Kimmey S, Calderon A, et al.
Immunity . 2020 Jul; 53(1):217-232.e5. PMID: 32668225
B cells are capable of a wide range of effector functions including antibody secretion, antigen presentation, cytokine production, and generation of immunological memory. A consistent strategy for classifying human B...
8.
Mitchell P, Salter B, Oliveria J, El-Gammal A, Tworek D, Smith S, et al.
Int Arch Allergy Immunol . 2018 Apr; 176(2):133-142. PMID: 29694974
Background: Previous murine models have demonstrated interleukin (IL)-33 to be an important mediator of type-2 inflammation and to promote airway hyperresponsiveness in allergic asthma. A number of inflammatory cells produce...
9.
Tang W, Smith S, Du W, Gugilla A, Du J, Oliveria J, et al.
Clin Transl Allergy . 2018 Feb; 8:5. PMID: 29456832
Background: Eosinophil-lineage committed progenitor cells (EoP) migrate from the bone marrow and differentiate locally to provide an ongoing source of mature eosinophils in asthmatic inflammatory responses in the airways. Sputum...
10.
Salter B, Smith S, Mukherjee M, Plante S, Krisna S, Nusca G, et al.
Am J Respir Cell Mol Biol . 2017 Aug; 58(1):99-106. PMID: 28853918
Activated bronchial epithelial cells (BEC) release various alarmins, including thymic stromal lymphopoietin (TSLP), that drive type 2 inflammation. We hypothesize that BEC-derived factors promote in situ eosinophil differentiation and maturation,...