John P Aris
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Explore the profile of John P Aris including associated specialties, affiliations and a list of published articles.
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17
Citations
2596
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Recent Articles
1.
Brown J, Sexton-Stallone B, Li Y, Frey E, Treves S, Fahey F, et al.
Phys Med Biol
. 2020 Dec;
65(23):235025.
PMID: 33263312
Skeletal scintigraphy is most performed in pediatric patients using the radiopharmaceutical Tc labelled methylene diphosphonate (Tc-MDP). Reference biokinetic models for Tc-MDP indicate 50% of the administered activity is uniformly localized...
2.
Torres-Machorro A, Aris J, Pillus L
Nucleic Acids Res
. 2015 Jan;
43(3):1646-58.
PMID: 25628362
Catalytically active proteins with divergent dual functions are often described as 'moonlighting'. In this work we characterize a new, chromatin-based function of Lys20, a moonlighting protein that is well known...
3.
Aris J, Alvers A, Ferraiuolo R, Fishwick L, Hanvivatpong A, Hu D, et al.
Exp Gerontol
. 2013 Jan;
48(10):1107-19.
PMID: 23337777
We have previously shown that autophagy is required for chronological longevity in the budding yeast Saccharomyces cerevisiae. Here we examine the requirements for autophagy during extension of chronological life span...
4.
Klionsky D, Abdalla F, Abeliovich H, Abraham R, Acevedo-Arozena A, Adeli K, et al.
Autophagy
. 2012 Sep;
8(4):445-544.
PMID: 22966490
In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered...
5.
Aris J, Fishwick L, Marraffini M, Seo A, Leeuwenburgh C, Dunn Jr W
Subcell Biochem
. 2011 Nov;
57:161-86.
PMID: 22094422
Understanding how non-dividing cells remain viable over long periods of time, which may be decades in humans, is of central importance in understanding mechanisms of aging and longevity. The long-term...
6.
The UF family of hybrid phantoms of the developing human fetus for computational radiation dosimetry
Maynard M, Geyer J, Aris J, Shifrin R, Bolch W
Phys Med Biol
. 2011 Jul;
56(15):4839-79.
PMID: 21765203
Historically, the development of computational phantoms for radiation dosimetry has primarily been directed at capturing and representing adult and pediatric anatomy, with less emphasis devoted to models of the human...
7.
Seo A, Joseph A, Dutta D, Hwang J, Aris J, Leeuwenburgh C
J Cell Sci
. 2010 Oct;
123(Pt 15):2533-42.
PMID: 20940129
A decline in mitochondrial function plays a key role in the aging process and increases the incidence of age-related disorders. A deeper understanding of the intricate nature of mitochondrial dynamics,...
8.
Aris J, Elios M, Bimstein E, Wallet S, Cha S, Lakshmyya K, et al.
J Periodontol
. 2010 Jun;
81(10):1481-7.
PMID: 20572766
Background: The receptor for advanced glycation end products (RAGE) is a multiligand receptor expressed in a number of cell types, including gingival epithelia. RAGE mediates inflammation and induces cellular oxidative...
9.
Falcon A, Chen S, Wood M, Aris J
Mol Cell Biochem
. 2009 Jul;
333(1-2):99-108.
PMID: 19618123
Acs2p is one of two acetyl-coenzyme A synthetases in Saccharomyces cerevisiae. We have prepared and characterized a monoclonal antibody specific for Acs2p and find that Acs2p is localized primarily to...
10.
Alvers A, Wood M, Hu D, Kaywell A, Dunn Jr W, Aris J
Autophagy
. 2009 May;
5(6):847-9.
PMID: 19458476
Rapamycin is an antibiotic that stimulates autophagy in a wide variety of eukaryotes, including the budding yeast Saccharomyces cerevisiae. Low concentrations of rapamycin extend yeast chronological life span (CLS). We...