John Metcalfe
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Explore the profile of John Metcalfe including associated specialties, affiliations and a list of published articles.
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Articles
37
Citations
537
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Recent Articles
1.
Ghebrekristos Y, Ahmed A, Beylis N, Singh S, Opperman C, Naufal F, et al.
Antimicrob Agents Chemother
. 2025 Feb;
69(3):e0167124.
PMID: 39918315
Xpert MTB/RIF Ultra (Ultra)-detected rifampicin-resistant tuberculosis (TB) is often programmatically confirmed using MTBDR. There are limited data on discordant results, including when re-tested using newer methods, like FluoroType MTBDR (FT-MTBDR)...
2.
Katoto P, Bihehe D, Brand A, Mushi R, Kusinza A, Alwood B, et al.
Environ Health
. 2024 Jan;
23(1):6.
PMID: 38233832
Background: In low- and middle-income countries countries, millions of deaths occur annually from household air pollution (HAP), pulmonary tuberculosis (PTB), and HIV-infection. However, it is unknown whether HAP influences PTB...
3.
Derendinger B, Dippenaar A, De Vos M, Huo S, Alberts R, Tadokera R, et al.
Lancet Microbe
. 2023 Nov;
4(12):e972-e982.
PMID: 37931638
Background: Bedaquiline is a life-saving tuberculosis drug undergoing global scale-up. People at risk of weak tuberculosis drug regimens are a priority for novel drug access despite the potential source of...
4.
Katoto P, Bihehe D, Brand A, Mushi R, Kusinza A, Alwood B, et al.
Res Sq
. 2023 Oct;
PMID: 37886487
Background: In developing countries, millions of deaths occur annually from household air pollution (HAP), pulmonary tuberculosis (PTB), and HIV-infection. However, it is unknown whether HAP influences PTB risk among people...
5.
Rao P, Modi N, Nguyen N, Vu D, Xie Y, Gandhi M, et al.
Clin Pharmacokinet
. 2023 Mar;
62(3):375-398.
PMID: 36869170
Background And Objective: Quantifying exposure to drugs for personalized dose adjustment is of critical importance in patients with tuberculosis who may be at risk of treatment failure or toxicity due...
6.
Derendinger B, De Vos M, Pillay S, Venter R, Metcalfe J, Ghebrekristos Y, et al.
J Mol Diagn
. 2022 Feb;
24(5):494-502.
PMID: 35108607
Strengthening second-line drug-resistant tuberculosis (TB) detection is a priority. GenoType MTBDRplus VER 2.0 performance is reduced with non-recommended ramp rate usage (temperature change speed between PCR cycles); however, ramp rate's...
7.
Sinclair J, Edmundson C, Metcalfe J, Bottoms L, Atkins S, Bentley I
Int J Environ Res Public Health
. 2021 Sep;
18(17).
PMID: 34501831
The aim of the current study was to examine the efficacy of resisted sled-based training compared to traditional unresisted sprint training in terms of mediating improvements in speed, agility, and...
8.
Chawana T, Nhachi C, Nathoo K, Ngara B, Okochi H, Louie A, et al.
J Acquir Immune Defic Syndr
. 2021 Jun;
88(2):181-185.
PMID: 34117162
Background: Suboptimal adherence to antiretroviral therapy (ART) is responsible for most virologic failure among adolescents with HIV. Methods for objectively measuring adherence to ART are limited. This study assessed the...
9.
Reckers A, Wu A, Ong C, Gandhi M, Metcalfe J, Gerona R
J Antimicrob Chemother
. 2021 Apr;
76(7):1865-1873.
PMID: 33864090
Background: As global confirmed cases and deaths from coronavirus disease 2019 (COVID-19) surpass 100 and 2.2 million, respectively, quantifying the effects of the widespread treatment of remdesivir (GS-5734, Veklury) and...
10.
Reckers A, Huo S, Esmail A, Dheda K, Bacchetti P, Gandhi M, et al.
J Chromatogr B Analyt Technol Biomed Life Sci
. 2021 Mar;
1169:122467.
PMID: 33713954
New all-oral regimens for rifampin-resistant tuberculosis (RR-TB) are being scaled up globally. Measurement of drug concentrations in hair assesses long-term drug exposure. Delamanid (DLM) is likely to be a key...