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» Authors » Kusum Nathoo

Kusum Nathoo

Explore the profile of Kusum Nathoo including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 55
Citations 1230
Followers 0
Related Specialties
Infectious Diseases
General Medicine
Pediatrics
Top 10 Co-Authors
Rashida A Ferrand
Diana M Gibb
Hilda Mujuru
Grace McHugh
Shungu Munyati
Tsitsi Bandason
Andrew J Prendergast
Victor Musiime
A Sarah Walker
James Hakim
Published In
Clin Infect Dis
AIDS
Pediatr Infect Dis J
PLoS Med
Trop Med Int Health
Affiliations
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Recent Articles
1.
Severe acute malnutrition promotes bacterial binding over proinflammatory cytokine secretion by circulating innate immune cells
Phiri T, Mutasa K, Rukobo S, Govha M, Mushayanembwa P, Mwakamui S, et al.
Sci Adv . 2023 Nov; 9(44):eadh2284. PMID: 37910623
Children with severe acute malnutrition (SAM) have high infectious mortality and morbidity, implicating defects in their immune defenses. We hypothesized that circulating innate immune cells from children (0 to 59...
2.
Growth improvement following antiretroviral therapy initiation in children with perinatally-acquired HIV diagnosed in older childhood in Zimbabwe: a prospective cohort study
Simms V, McHugh G, Dauya E, Bandason T, Mujuru H, Nathoo K, et al.
BMC Pediatr . 2022 Jul; 22(1):446. PMID: 35879693
Background: Children who initiate antiretroviral therapy (ART) before age 5 years can recover height and weight compared to uninfected peers, but growth outcomes are unknown for children initiating ART at...
3.
Enhanced surveillance for adverse events following immunization during the 2019 typhoid conjugate vaccine campaign in Harare, Zimbabwe
Shaum A, Mujuru H, Takamiya M, Ticklay I, Nathoo K, Sreenivasan N, et al.
Vaccine . 2022 May; 40(26):3573-3580. PMID: 35568590
Background: During February 25-March 4, 2019, Zimbabwe's Ministry of Health and Child Care conducted an emergency campaign using 342,000 doses of typhoid conjugate vaccine (TCV) targeting individuals 6 months-15 years...
4.
Delays in presentation of intussusception and development of gangrene in Zimbabwe
Mazingi D, Burnett E, Mujuru H, Nathoo K, Tate J, Mwenda J, et al.
Pan Afr Med J . 2021 Sep; 39(Suppl 1):3. PMID: 34548895
Introduction: prompt diagnosis and treatment are considered key to successful management of intussusception. We examined pre-treatment delay among intussusception cases in Zimbabwe and conducted an exploratory analysis of factors associated...
5.
Brief Report: Ritonavir Concentrations in Hair Predict Virologic Outcomes in HIV-Infected Adolescents With Virologic Failure on Atazanavir-Based or Ritonavir-Based Second-Line Treatment
Chawana T, Nhachi C, Nathoo K, Ngara B, Okochi H, Louie A, et al.
J Acquir Immune Defic Syndr . 2021 Jun; 88(2):181-185. PMID: 34117162
Background: Suboptimal adherence to antiretroviral therapy (ART) is responsible for most virologic failure among adolescents with HIV. Methods for objectively measuring adherence to ART are limited. This study assessed the...
6.
Short Communication: Higher Tenofovir Concentrations in Hair Are Associated with Decreases in Viral Load and Not Self-Reported Adherence in HIV-Infected Adolescents with Second-Line Virological Treatment Failure
Chawana T, Nhachi C, Nathoo K, Ngara B, Okochi H, Louie A, et al.
AIDS Res Hum Retroviruses . 2021 Jan; 37(10):748-750. PMID: 33499754
Objective methods of measuring antiretroviral adherence are limited. We assessed the relationship between tenofovir disoproxil fumarate (TDF) hair concentrations, self-reported adherence, and virological outcomes in HIV-infected adolescents in Harare, Zimbabwe....
7.
Pharmacokinetics and Safety of Zidovudine, Lamivudine, and Lopinavir/Ritonavir in HIV-infected Children With Severe Acute Malnutrition in Sub-Saharan Africa: IMPAACT Protocol P1092
Owor M, Tierney C, Ziemba L, Browning R, Moye J, Graham B, et al.
Pediatr Infect Dis J . 2021 Jan; 40(5):446-452. PMID: 33464021
Background: Severe acute malnutrition (SAM) may alter the pharmacokinetics (PK), efficacy, and safety of antiretroviral therapy. The phase IV study, IMPAACT P1092, compared PK, safety, and tolerability of zidovudine (ZDV),...
8.
Understanding Ethical, Legal and Societal Issues (ELSIs) in Human Biobanking and Genomics for Research and Healthcare in Zimbabwe: The Genomics Inheritance Law Ethics and Society (GILES) initiative
Matimba A, Chimatira A, Kuguyo O, January J, Mupambireyi Z, Marimbe-Dube B, et al.
AAS Open Res . 2020 May; 2:1. PMID: 32382699
Biobanks and human genomics applications are key for understanding health, disease and heredity in Africa and globally. Growing interest in these technologies calls for strengthening relevant legal, ethical and policy...
9.
Carotid intima media thickness in older children and adolescents with HIV taking antiretroviral therapy
Majonga E, Chiesa S, McHugh G, Mujuru H, Nathoo K, Odland J, et al.
Medicine (Baltimore) . 2020 Apr; 99(17):e19554. PMID: 32332603
Increased carotid intima-media thickness (cIMT) is reported in both adults and children with human immunodeficiency virus (HIV) in high income settings and is associated with an increased risk of cardiovascular...
10.
Evaluating an enhanced adherence intervention among HIV positive adolescents failing atazanavir/ritonavir-based second line antiretroviral treatment at a public health clinic
Chawana T, Katzenstein D, Nathoo K, Ngara B, Nhachi C
J AIDS HIV Res . 2019 Oct; 9(1):17-30. PMID: 31649827
Methods: HIV-positive adolescents (10-18 years) on ATV/r-based 2 line treatment with virological failure (viral load (VL) ≥1 000 copies/ml) were randomized to either standard care (SC) or SC with addition...