John Lowengrub
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Explore the profile of John Lowengrub including associated specialties, affiliations and a list of published articles.
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62
Citations
1143
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Recent Articles
1.
Olaranont N, Wei C, Lowengrub J, Wu M
ArXiv
. 2024 Dec;
PMID: 39679269
It is widely recognized that reciprocal interactions between cells and their microenvironment, via mechanical forces and biochemical signaling pathways, regulate cell behaviors during normal development, homeostasis and disease progression such...
2.
Duan J, Ngo M, Karri S, Tsoi L, Gudjonsson J, Shahbaba B, et al.
Nat Commun
. 2024 May;
15(1):3840.
PMID: 38714698
As the circadian clock regulates fundamental biological processes, disrupted clocks are often observed in patients and diseased tissues. Determining the circadian time of the patient or the tissue of focus...
3.
Butner J, Dogra P, Chung C, Pasqualini R, Arap W, Lowengrub J, et al.
Nat Comput Sci
. 2023 Dec;
2(12):785-796.
PMID: 38126024
Encouraging advances are being made in cancer immunotherapy modeling, especially in the key areas of developing personalized treatment strategies based on individual patient parameters, predicting treatment outcomes and optimizing immunotherapy...
4.
Rodriguez J, Iniguez A, Jena N, Tata P, Liu Z, Lander A, et al.
Elife
. 2023 Apr;
12.
PMID: 37115622
Chronic myeloid leukemia (CML) is a blood cancer characterized by dysregulated production of maturing myeloid cells driven by the product of the Philadelphia chromosome, the BCR-ABL1 tyrosine kinase. Tyrosine kinase...
5.
Xiao W, Liu K, Lowengrub J, Li S, Zhao M
Phys Rev E
. 2023 Apr;
107(3-2):035103.
PMID: 37072945
We study the wrinkling dynamics of three-dimensional vesicles in a time-dependent elongation flow by utilizing an immersed boundary method. For a quasispherical vesicle, our numerical results well match the predictions...
6.
Duan J, Ngo M, Karri S, Tsoi L, Gudjonsson J, Shahbaba B, et al.
bioRxiv
. 2023 Apr;
PMID: 37066246
As the circadian clock regulates fundamental biological processes, disrupted clocks are often observed in patients and diseased tissues. Determining the circadian time of the patient or the tissue of focus...
7.
Bilic P, Christ P, Li H, Vorontsov E, Ben-Cohen A, Kaissis G, et al.
Med Image Anal
. 2022 Dec;
84:102680.
PMID: 36481607
In this work, we report the set-up and results of the Liver Tumor Segmentation Benchmark (LiTS), which was organized in conjunction with the IEEE International Symposium on Biomedical Imaging (ISBI)...
8.
Zheng X, Zhao K, Jackson T, Lowengrub J
J Math Biol
. 2022 Jul;
85(1):5.
PMID: 35796898
We study a classic Darcy's law model for tumor cell motion with inhomogeneous and isotropic conductivity. The tumor cells are assumed to be a constant density fluid flowing through porous...
9.
Yan H, Ramirez-Guerrero D, Lowengrub J, Wu M
PLoS Comput Biol
. 2022 Jun;
18(6):e1010288.
PMID: 35737645
[This corrects the article DOI: 10.1371/journal.pcbi.1009701.].
10.
Uhl P, Lowengrub J, Komarova N, Wodarz D
PLoS Comput Biol
. 2022 May;
18(5):e1010039.
PMID: 35522694
Feedback mechanisms within cell lineages are thought to be important for maintaining tissue homeostasis. Mathematical models that assume well-mixed cell populations, together with experimental data, have suggested that negative feedback...