» Articles » PMID: 36481607

The Liver Tumor Segmentation Benchmark (LiTS)

Overview
Journal Med Image Anal
Publisher Elsevier
Specialty Radiology
Date 2022 Dec 8
PMID 36481607
Authors
Affiliations
Soon will be listed here.
Abstract

In this work, we report the set-up and results of the Liver Tumor Segmentation Benchmark (LiTS), which was organized in conjunction with the IEEE International Symposium on Biomedical Imaging (ISBI) 2017 and the International Conferences on Medical Image Computing and Computer-Assisted Intervention (MICCAI) 2017 and 2018. The image dataset is diverse and contains primary and secondary tumors with varied sizes and appearances with various lesion-to-background levels (hyper-/hypo-dense), created in collaboration with seven hospitals and research institutions. Seventy-five submitted liver and liver tumor segmentation algorithms were trained on a set of 131 computed tomography (CT) volumes and were tested on 70 unseen test images acquired from different patients. We found that not a single algorithm performed best for both liver and liver tumors in the three events. The best liver segmentation algorithm achieved a Dice score of 0.963, whereas, for tumor segmentation, the best algorithms achieved Dices scores of 0.674 (ISBI 2017), 0.702 (MICCAI 2017), and 0.739 (MICCAI 2018). Retrospectively, we performed additional analysis on liver tumor detection and revealed that not all top-performing segmentation algorithms worked well for tumor detection. The best liver tumor detection method achieved a lesion-wise recall of 0.458 (ISBI 2017), 0.515 (MICCAI 2017), and 0.554 (MICCAI 2018), indicating the need for further research. LiTS remains an active benchmark and resource for research, e.g., contributing the liver-related segmentation tasks in http://medicaldecathlon.com/. In addition, both data and online evaluation are accessible via https://competitions.codalab.org/competitions/17094.

Citing Articles

Rethinking model prototyping through the MedMNIST+ dataset collection.

Doerrich S, Di Salvo F, Brockmann J, Ledig C Sci Rep. 2025; 15(1):7669.

PMID: 40044786 PMC: 11883007. DOI: 10.1038/s41598-025-92156-9.


Systematic Review: AI Applications in Liver Imaging with a Focus on Segmentation and Detection.

Pomohaci M, Grasu M, Baicoianu-Nitescu A, Enache R, Lupescu I Life (Basel). 2025; 15(2).

PMID: 40003667 PMC: 11856300. DOI: 10.3390/life15020258.


Anatomically Guided Deep Learning System for Right Internal Jugular Line (RIJL) Segmentation and Tip Localization in Chest X-Ray.

Wei S, Shrestha L, Melendez-Corres G, Brown M Life (Basel). 2025; 15(2).

PMID: 40003610 PMC: 11856827. DOI: 10.3390/life15020201.


Automatic future remnant segmentation in liver resection planning.

Messaoudi H, Abbas M, Badic B, Ben Salem D, Belaid A, Conze P Int J Comput Assist Radiol Surg. 2025; .

PMID: 39961898 DOI: 10.1007/s11548-025-03331-2.


Enhancing unsupervised learning in medical image registration through scale-aware context aggregation.

Liu Y, Wang L, Ning X, Gao Y, Wang D iScience. 2025; 28(2):111734.

PMID: 39898031 PMC: 11787544. DOI: 10.1016/j.isci.2024.111734.


References
1.
Shiina S, Sato K, Tateishi R, Shimizu M, Ohama H, Hatanaka T . Percutaneous Ablation for Hepatocellular Carcinoma: Comparison of Various Ablation Techniques and Surgery. Can J Gastroenterol Hepatol. 2018; 2018:4756147. PMC: 6008833. DOI: 10.1155/2018/4756147. View

2.
Xu Z, Burke R, Lee C, Baucom R, Poulose B, Abramson R . Efficient multi-atlas abdominal segmentation on clinically acquired CT with SIMPLE context learning. Med Image Anal. 2015; 24(1):18-27. PMC: 4532551. DOI: 10.1016/j.media.2015.05.009. View

3.
Linguraru M, Richbourg W, Liu J, Watt J, Pamulapati V, Wang S . Tumor burden analysis on computed tomography by automated liver and tumor segmentation. IEEE Trans Med Imaging. 2012; 31(10):1965-76. PMC: 3924860. DOI: 10.1109/TMI.2012.2211887. View

4.
Albain K, Swann R, Rusch V, Turrisi 3rd A, Shepherd F, Smith C . Radiotherapy plus chemotherapy with or without surgical resection for stage III non-small-cell lung cancer: a phase III randomised controlled trial. Lancet. 2009; 374(9687):379-86. PMC: 4407808. DOI: 10.1016/S0140-6736(09)60737-6. View

5.
Li H, Jiang G, Zhang J, Wang R, Wang Z, Zheng W . Fully convolutional network ensembles for white matter hyperintensities segmentation in MR images. Neuroimage. 2018; 183:650-665. DOI: 10.1016/j.neuroimage.2018.07.005. View