John L Rustad
Overview
Explore the profile of John L Rustad including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
164
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Recent Articles
1.
Denorme F, Armstrong N, Stoller M, Portier I, Tugolukova E, Tanner R, et al.
J Clin Invest
. 2023 Jul;
133(18).
PMID: 37471144
Protease-activated receptor 4 (PAR4) (gene F2RL3) harbors a functional dimorphism, rs773902 A/G (encoding Thr120/Ala120, respectively) and is associated with greater platelet aggregation. The A allele frequency is more common in...
2.
de Araujo C, Denorme F, Stephens W, Li Q, Cody M, Crandell J, et al.
Front Immunol
. 2023 Apr;
14:1171222.
PMID: 37063850
[This corrects the article DOI: 10.3389/fimmu.2022.1046574.].
3.
de Araujo C, Denorme F, Stephens W, Li Q, Cody M, Crandell J, et al.
Front Immunol
. 2023 Feb;
13:1046574.
PMID: 36733389
Introduction: Neutrophil extracellular traps (NETs) clear pathogens but may contribute Q8 pathogenically to host inflammatory tissue damage during sepsis. Innovative therapeutic agents targeting NET formation and their potentially harmful collateral...
4.
Bounajem M, Denorme F, Rustad J, Campbell R, Grandhi R
Diagnostics (Basel)
. 2022 Dec;
12(12).
PMID: 36552941
Non-acute subdural hematomas (NASHs) are a cause of significant morbidity and mortality, particularly with recurrences. Although recurrence is believed to involve a disordered neuroinflammatory cascade involving vascular endothelial growth factor...
5.
Denorme F, Rustad J, Portier I, Crandell J, de Araujo C, Cody M, et al.
Pediatr Res
. 2022 Jul;
93(4):862-869.
PMID: 35902703
Background: Treatment of neonatal peritonitis and sepsis is challenging. Following infection, neutrophils elaborate neutrophil extracellular traps (NETs)-extracellular lattices of decondensed chromatin decorated with antimicrobial proteins. NETs, however, can augment pathogenic...
6.
Denorme F, Portier I, Rustad J, Cody M, de Araujo C, Hoki C, et al.
J Clin Invest
. 2022 Mar;
132(10).
PMID: 35358095
Ischemic stroke prompts a strong inflammatory response, which is associated with exacerbated outcomes. In this study, we investigated mechanistic regulators of neutrophil extracellular trap (NET) formation in stroke and whether...
7.
Campbell R, Campbell H, Bircher J, de Araujo C, Denorme F, Crandell J, et al.
Blood
. 2021 Jun;
138(11):977-988.
PMID: 34192300
Neutrophil extracellular traps (NETs) are important components of innate immunity. Neonatal neutrophils (polymorphonuclear leukocytes [PMNs]) fail to form NETs due to circulating NET-inhibitory peptides (NIPs), cleavage fragments of α1-antitrypsin (A1AT)....
8.
Denorme F, Rustad J, Campbell R
Curr Opin Hematol
. 2021 Jun;
28(5):301-307.
PMID: 34183536
Purpose Of Review: In this review, we will describe how the combined ability of platelets and neutrophils to interact with each other drives ischemic stroke brain injury. Recent Findings: Neutrophils...