Irina Portier
Overview
Explore the profile of Irina Portier including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
1755
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Recent Articles
1.
Portier I, Manne B, Kosaka Y, Tolley N, Denorme F, Babur O, et al.
J Thromb Haemost
. 2024 Jun;
22(9):2576-2588.
PMID: 38849085
Background: Aging is an independent risk factor for the development of cardiovascular, thrombotic, and other chronic diseases. However, mechanisms of platelet hyperactivation in aging remain poorly understood. Objectives: Here, we...
2.
3.
Portier I, Andrianova I, Campbell R
J Thromb Haemost
. 2023 Nov;
22(2):311-314.
PMID: 37940049
No abstract available.
4.
Denorme F, Armstrong N, Stoller M, Portier I, Tugolukova E, Tanner R, et al.
J Clin Invest
. 2023 Jul;
133(18).
PMID: 37471144
Protease-activated receptor 4 (PAR4) (gene F2RL3) harbors a functional dimorphism, rs773902 A/G (encoding Thr120/Ala120, respectively) and is associated with greater platelet aggregation. The A allele frequency is more common in...
5.
Guo L, Jacob S, Manne B, Kolawole E, Guo S, Wang X, et al.
Haematologica
. 2023 Jul;
109(1):331-336.
PMID: 37439340
No abstract available.
6.
Manne B, Campbell R, Bhatlekar S, Ajanel A, Denorme F, Portier I, et al.
Blood
. 2022 Aug;
140(23):2477-2489.
PMID: 35930749
The MAPK-interacting kinase (Mnk) family includes Mnk1 and Mnk2, which are phosphorylated and activated in response to extracellular stimuli. Mnk1 contributes to cellular responses by regulating messenger RNA (mRNA) translation,...
7.
Denorme F, Rustad J, Portier I, Crandell J, de Araujo C, Cody M, et al.
Pediatr Res
. 2022 Jul;
93(4):862-869.
PMID: 35902703
Background: Treatment of neonatal peritonitis and sepsis is challenging. Following infection, neutrophils elaborate neutrophil extracellular traps (NETs)-extracellular lattices of decondensed chromatin decorated with antimicrobial proteins. NETs, however, can augment pathogenic...
8.
Denorme F, Portier I, Rustad J, Cody M, de Araujo C, Hoki C, et al.
J Clin Invest
. 2022 Mar;
132(10).
PMID: 35358095
Ischemic stroke prompts a strong inflammatory response, which is associated with exacerbated outcomes. In this study, we investigated mechanistic regulators of neutrophil extracellular trap (NET) formation in stroke and whether...
9.
Schwertz H, Rowley J, Portier I, Middleton E, Tolley N, Campbell R, et al.
Autophagy
. 2021 Oct;
18(7):1534-1550.
PMID: 34689707
Platelets mediate central aspects of host responses during sepsis, an acute profoundly systemic inflammatory response due to infection. Macroautophagy/autophagy, which mediates critical aspects of cellular responses during inflammatory conditions, is...
10.
Queisser K, Mellema R, Middleton E, Portier I, Manne B, Denorme F, et al.
JCI Insight
. 2021 Jul;
6(17).
PMID: 34314391
Vascular injury has emerged as a complication contributing to morbidity in coronavirus disease 2019 (COVID-19). The glycosaminoglycan hyaluronan (HA) is a major component of the glycocalyx, a protective layer of...