John L Black
Overview
Explore the profile of John L Black including associated specialties, affiliations and a list of published articles.
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37
Citations
713
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Recent Articles
1.
Safgren S, Suman V, Leon Ferre R, Kosel M, Stearns V, Henry N, et al.
Breast Cancer Res Treat
. 2025 Feb;
PMID: 40011368
Purpose: Tamoxifen undergoes metabolic activation by cytochrome P450 (CYP) enzymes to metabolites with more potent anti-estrogenic effects. Numerous studies demonstrate decreased tamoxifen efficacy associated with reduced CYP2D6 activity or lower...
2.
Sterner R, Hall P, Matern D, Black J, Moyer A
J Mol Diagn
. 2024 Aug;
26(11):988-994.
PMID: 39182670
Thiopurine 6-mercaptopurine (6-MP) is metabolized by thiopurine methyl transferase (TPMT). TPMT genetic variation results in some individuals having reduced or absent TPMT enzyme activity. If these individuals take a full...
3.
Atiq M, Peterson S, Langman L, Baudhuin L, Black J, Moyer A
J Pers Med
. 2023 Jun;
13(6).
PMID: 37373874
duplication has important pharmacogenomic implications. Reflex testing with long-range PCR (LR-PCR) can resolve the genotype when a duplication and alleles with differing activity scores are detected. We evaluated whether visual...
4.
Niknafs S, Fortes M, Cho S, Black J, Roura E
BMC Genomics
. 2022 May;
23(1):393.
PMID: 35606689
Background: The rate of protein accretion and growth affect amino acid requirements in young animals. Differences in amino acid metabolism contribute to individual variations in growth rate. This study aimed...
5.
Moyer A, Langman L, Black J
Clin Chem
. 2022 Jan;
68(5):616-618.
PMID: 35021195
No abstract available.
6.
Matey E, Ragan A, Oyen L, Vitek C, Aoudia S, Ragab A, et al.
Pharmacogenomics J
. 2021 Oct;
22(1):69-74.
PMID: 34671112
Purpose: The Pharmacogenomics (PGx) Profile Service was a proof-of-concept project to implement PGx in patient care at Mayo Clinic. Methods: Eighty-two healthy individuals aged 18 and older underwent genotyping of...
7.
Ratanpaul V, Zhang D, Williams B, Diffey S, Black J, Gidley M
Eur J Nutr
. 2021 May;
60(7):4001-4017.
PMID: 33950401
Purpose: The combined effects of grain digestibility and dietary fibre on digesta passage rate and satiety in humans are poorly understood. Satiety can be increased through gastric distention, reduced gastric...
8.
Black J, Davison T, Box I
Animals (Basel)
. 2021 Apr;
11(4).
PMID: 33805324
Anthropomorphic greenhouse gases are raising the temperature of the earth and threatening ecosystems. Since 1950 atmospheric carbon dioxide has increased 28%, while methane has increased 70%. Methane, over the first...
9.
Davison T, Black J, Moss J
Anim Front
. 2020 Nov;
10(4):14-21.
PMID: 33150007
No abstract available.
10.
Morales-Rosado J, Goel K, Zhang L, Akerblom A, Baheti S, Black J, et al.
Cardiovasc Drugs Ther
. 2020 Jul;
35(3):549-559.
PMID: 32623598
Purpose: Describe CYP2C19 sequencing results in the largest series of clopidogrel-treated cases with stent thrombosis (ST), the closest clinical phenotype to clopidogrel resistance. Evaluate the impact of CYP2C19 genetic variation...