Wayne T Nicholson
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Explore the profile of Wayne T Nicholson including associated specialties, affiliations and a list of published articles.
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67
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1475
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Recent Articles
1.
Dillon G, Harvey R, Limberg J, Nicholson W, Joyner M, Baker S, et al.
J Physiol
. 2025 Feb;
PMID: 40012199
Menopause is associated with vascular dysfunction. During the menopausal transition, endogenous oestradiol concentrations diminish. Oestradiol is vasoprotective because it has direct and indirect effects on the vasculature. The present study...
2.
Klassen S, Limberg J, Harvey R, Wiggins C, Spafford J, Iannarelli N, et al.
Am J Physiol Heart Circ Physiol
. 2024 Oct;
327(6):H1599-H1605.
PMID: 39453430
What is the purpose of sympathetic neuronal action potential (AP) discharge and recruitment patterns for human vascular regulation? This study tested the hypothesis that sympathetic neuronal discharge and recruitment patterns...
3.
Boyes N, Klassen S, Baker S, Nicholson W, Joyner M, Shoemaker J, et al.
J Neurophysiol
. 2024 Aug;
132(3):1087-1097.
PMID: 39140588
Efferent muscle sympathetic nerve activity (MSNA) is under tonic baroreflex control. The arterial baroreflex exerts the strongest influence over medium-sized sympathetic action potential (AP) subpopulations in efferent MSNA recordings. Prior...
4.
Klassen S, Limberg J, Harvey R, Wiggins C, Iannarelli N, Senefeld J, et al.
J Physiol
. 2024 Jul;
602(16):4053-4071.
PMID: 39058701
The present study investigated the impact of central α-adrenergic mechanisms on sympathetic action potential (AP) discharge, recruitment and latency strategies. We used the microneurographic technique to record muscle sympathetic nerve...
5.
Kosaski D, Cole K, Wright J, El Melik R, Kung S, Nicholson W, et al.
Ment Health Clin
. 2023 Dec;
13(6):303-310.
PMID: 38058598
Introduction: Although there are studies assessing reasons for antidepressant discontinuation, little is known about the impact of sex differences or cytochrome P450 phenotypes. Our objective is to assess discontinuation rates...
6.
Wang L, Scherer S, Bielinski S, Muzny D, Jones L, Black 3rd J, et al.
Genet Med
. 2022 Mar;
24(5):1062-1072.
PMID: 35331649
Purpose: The Mayo-Baylor RIGHT 10K Study enabled preemptive, sequence-based pharmacogenomics (PGx)-driven drug prescribing practices in routine clinical care within a large cohort. We also generated the tools and resources necessary...
7.
Wright J, Moyer A, Sutton J, Chaney A, Nicholson W, El Melik R, et al.
Pharmacogenomics
. 2021 Nov;
22(18):1177-1183.
PMID: 34747639
Pharmacogenomics (PGx) tests are performed on whole-blood or saliva specimens. In patients with a transplanted liver, PGx results may be discordant with hepatic drug metabolizing enzyme activity. We evaluate the...
8.
Matey E, Ragan A, Oyen L, Vitek C, Aoudia S, Ragab A, et al.
Pharmacogenomics J
. 2021 Oct;
22(1):69-74.
PMID: 34671112
Purpose: The Pharmacogenomics (PGx) Profile Service was a proof-of-concept project to implement PGx in patient care at Mayo Clinic. Methods: Eighty-two healthy individuals aged 18 and older underwent genotyping of...
9.
Bishop J, Huang R, Brown J, Mroz P, Johnson S, Allen J, et al.
Pharmacogenomics
. 2021 Jun;
22(11):681-691.
PMID: 34137665
Several healthcare organizations across Minnesota have developed formal pharmacogenomic (PGx) clinical programs to increase drug safety and effectiveness. Healthcare professional and student education is strong and there are multiple opportunities...
10.
Senefeld J, Klassen S, Ford S, Senese K, Wiggins C, Bostrom B, et al.
Transfusion
. 2021 May;
61(8):2503-2511.
PMID: 34036587
In the absence of effective countermeasures, human convalescent plasma has been widely used to treat severe acute respiratory syndrome coronavirus 2, the causative agent of novel coronavirus disease 19 (COVID-19),...