John C Rogers
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Explore the profile of John C Rogers including associated specialties, affiliations and a list of published articles.
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48
Citations
1436
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Recent Articles
1.
Li J, Cai Z, Bomgarden R, Pike I, Kuhn K, Rogers J, et al.
J Proteome Res
. 2021 Apr;
20(5):2964-2972.
PMID: 33900084
The development of the TMTpro-16plex series expanded the breadth of commercial isobaric tagging reagents by nearly 50% over classic TMT-11plex. In addition to the described 16plex reagents, the proline-based TMTpro...
2.
Ordureau A, Yu Q, Bomgarden R, Rogers J, Harper J, Gygi S, et al.
J Proteome Res
. 2021 Mar;
20(5):3009-3013.
PMID: 33689365
Stable isotope labeling is a leading strategy for mass-spectrometry-based peptide quantification. Whereas TMTpro isobaric tagging can quantify up to 16 multiplexed samples in a single experiment, nonisobaric, yet chromatographically indistinguishable,...
3.
Wilson M, Tzeng S, Augustin M, Meyer M, Jiang X, Choi J, et al.
Mol Cell Proteomics
. 2021 Mar;
20:100063.
PMID: 33677124
Protein phosphorylation is one of the most prevalent posttranslational modifications found in eukaryotic systems. It serves as a key molecular mechanism that regulates protein function in response to environmental stimuli....
4.
Li J, Van Vranken J, Vaites L, Schweppe D, Huttlin E, Etienne C, et al.
Nat Methods
. 2020 Mar;
17(4):399-404.
PMID: 32203386
Isobaric labeling empowers proteome-wide expression measurements simultaneously across multiple samples. Here an expanded set of 16 isobaric reagents based on an isobutyl-proline immonium ion reporter structure (TMTpro) is presented. These...
5.
Wang X, Mooradian A, Erdmann-Gilmore P, Zhang Q, Viner R, Davies S, et al.
Sci Signal
. 2017 Aug;
10(491).
PMID: 28790197
Cancer forms specialized microenvironmental niches that promote local invasion and colonization. Engrafted patient-derived xenografts (PDXs) locally invade and colonize naïve stroma in mice while enabling unambiguous molecular discrimination of human...
6.
Rogers J, Bomgarden R
Adv Exp Med Biol
. 2016 Dec;
919:43-62.
PMID: 27975212
Mass spectrometry (MS) has become the predominant technology to analyze proteins due to it ability to identify and characterize proteins and their modifications with high sensitivity and selectivity (Aebersold and...
7.
Zhou S, Hu Y, Veillon L, Snovida S, Rogers J, Saba J, et al.
Anal Chem
. 2016 Jul;
88(15):7515-22.
PMID: 27377957
Protein glycosylation plays an important role in various biological processes, such as modification of protein function, regulation of protein-protein interactions, and control of turnover rates of proteins. Moreover, glycans have...
8.
Afiuni-Zadeh S, Rogers J, Snovida S, Bomgarden R, Griffin T
Biotechniques
. 2016 Apr;
60(4):186-8, 190, 192-6.
PMID: 27071607
Protein carbonylation is a common oxidative stress (OS)-driven post-translational modification (PTM). Proteome-wide carbonylation events can best be characterized using a combination of analytical approaches. Immunoblotting of carbonylated proteins provides data...
9.
Huang W, Rogers J, Nelson E, Wright C, Teal C
Fam Med
. 2016 Apr;
48(4):294-9.
PMID: 27057608
Background And Objectives: Reflection after patient encounters is an important aspect of clinical learning. After our medical school instituted a reflection paper assignment for all clerkships, we wanted to learn...
10.
Chung H, Murray C, Venkatraman V, Crowgey E, Rainer P, Cole R, et al.
Circ Res
. 2015 Sep;
117(10):846-57.
PMID: 26338901
Rationale: S-nitrosylation (SNO), an oxidative post-translational modification of cysteine residues, responds to changes in the cardiac redox-environment. Classic biotin-switch assay and its derivatives are the most common methods used for...