John A Katzenellenbogen
Overview
Explore the profile of John A Katzenellenbogen including associated specialties, affiliations and a list of published articles.
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280
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6898
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Recent Articles
11.
Katzenellenbogen B, Guillen V, Katzenellenbogen J
Breast Cancer Res
. 2023 Jun;
25(1):76.
PMID: 37370117
FOXM1 (Forkhead box M1) is an oncogenic transcription factor that is greatly upregulated in breast cancer and many other cancers where it promotes tumorigenesis, and cancer growth and progression. It...
12.
Katzenellenbogen J
Proc Natl Acad Sci U S A
. 2023 Mar;
120(11):e2300608120.
PMID: 36877834
No abstract available.
13.
Guillen V, Ziegler Y, Gopinath C, Kumar S, Dey P, Plotner B, et al.
Breast Cancer Res Treat
. 2023 Feb;
198(3):607-621.
PMID: 36847915
Purpose: Few targeted treatment options currently exist for patients with advanced, often recurrent breast cancers, both triple-negative breast cancer (TNBC) and hormone receptor-positive breast cancer. Forkhead box M1 (FOXM1) is...
14.
Zhou D, Chu W, Xu J, Schwarz S, Katzenellenbogen J
Sci Rep
. 2023 Feb;
13(1):3182.
PMID: 36823435
Positron emission tomography (PET) is an in vivo imaging technology that utilizes positron-emitting radioisotope-labeled compounds as PET radiotracers that are commonly used in clinic and in various research areas, including...
15.
Nandi I, Smith H, Sanguin-Gendreau V, Ji L, Pacis A, Papavasiliou V, et al.
J Clin Invest
. 2023 Feb;
133(7).
PMID: 36795481
Activation of the tyrosine kinase c-Src promotes breast cancer progression and poor outcomes, yet the underlying mechanisms are incompletely understood. Here, we have shown that deletion of c-Src in a...
16.
Dey P, Wang A, Ziegler Y, Kumar S, Yan S, Kim S, et al.
Endocrinology
. 2022 Oct;
163(12).
PMID: 36251879
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer characterized by the absence of estrogen receptor alpha, progesterone receptor, and HER2. These receptors often serve as targets in...
17.
Xu J, Chen H, Rogers B, Katzenellenbogen J, Zhou D
Nucl Med Biol
. 2022 Oct;
114-115:65-70.
PMID: 36193598
Introduction: Solid-phase synthesis and conjugation reactions of acids and amines using coupling reagents are common in organic synthesis, but rare in F radiochemistry. 4-[F]Fluorobenzoic acid (FBA) is a useful building...
18.
Doepner M, Lee I, Natale C, Brathwaite R, Venkat S, Kim S, et al.
Sci Adv
. 2022 Sep;
8(35):eabn4007.
PMID: 36054350
Melanoma risk is 30 times higher in people with lightly pigmented skin versus darkly pigmented skin. Using primary human melanocytes representing the full human skin pigment continuum and preclinical melanoma...
19.
Cheng Y, Sun F, Thornton K, Jing X, Dong J, Yun G, et al.
Oncogene
. 2022 Jul;
41(32):3899-3911.
PMID: 35794249
The transcription factor, forkhead box M1 (FOXM1), has been implicated in the natural history and outcome of newly diagnosed high-risk myeloma (HRMM) and relapsed/refractory myeloma (RRMM), but the mechanism with...
20.
Ziegler Y, Guillen V, Kim S, Katzenellenbogen J, Katzenellenbogen B
Cancers (Basel)
. 2021 Dec;
13(24).
PMID: 34944900
Forkhead box M1 (FOXM1), an oncogenic transcription factor associated with aggressiveness and highly expressed in many cancers, is an emerging therapeutic target. Using novel 1,1-diarylethylene-diammonium small molecule FOXM1 inhibitors, we...