Johannes Meisig
Overview
Explore the profile of Johannes Meisig including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
18
Citations
1945
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Steinbrecht D, Minia I, Milek M, Meisig J, Bluthgen N, Landthaler M
Mol Syst Biol
. 2024 Nov;
20(12):1346-1371.
PMID: 39548324
Eukaryotic mRNAs are transcribed, processed, translated, and degraded in different subcellular compartments. Here, we measured mRNA flow rates between subcellular compartments in mouse embryonic stem cells. By combining metabolic RNA...
2.
Seidel F, Cherianidou A, Kappenberg F, Marta M, Dreser N, Blum J, et al.
Cells
. 2022 Nov;
11(21).
PMID: 36359802
Human-relevant tests to predict developmental toxicity are urgently needed. A currently intensively studied approach makes use of differentiating human stem cells to measure chemically-induced deviations of the normal developmental program,...
3.
Cherianidou A, Seidel F, Kappenberg F, Dreser N, Blum J, Waldmann T, et al.
Chem Res Toxicol
. 2022 Apr;
35(5):760-773.
PMID: 35416653
Despite the progress made in developmental toxicology, there is a great need for in vitro tests that identify developmental toxicants in relation to human oral doses and blood concentrations. In...
4.
Meisig J, Dreser N, Kapitza M, Henry M, Rotshteyn T, Rahnenfuhrer J, et al.
Nucleic Acids Res
. 2020 Nov;
48(22):12577-12592.
PMID: 33245762
Thousands of transcriptome data sets are available, but approaches for their use in dynamic cell response modelling are few, especially for processes affected simultaneously by two orthogonal influencing variables. We...
5.
Dreser N, Madjar K, Holzer A, Kapitza M, Scholz C, Kranaster P, et al.
Arch Toxicol
. 2019 Nov;
94(1):151-171.
PMID: 31712839
The first in vitro tests for developmental toxicity made use of rodent cells. Newer teratology tests, e.g. developed during the ESNATS project, use human cells and measure mechanistic endpoints (such...
6.
Meisig J, Bluthgen N
Philos Trans R Soc Lond B Biol Sci
. 2018 May;
373(1750).
PMID: 29786557
A large body of data have accumulated that characterize the gene regulatory network of stem cells. Yet, a comprehensive and integrative understanding of this complex network is lacking. Network reverse...
7.
Uhlitz F, Sieber A, Wyler E, Fritsche-Guenther R, Meisig J, Landthaler M, et al.
Mol Syst Biol
. 2017 Sep;
13(9):944.
PMID: 28947433
No abstract available.
8.
Uhlitz F, Sieber A, Wyler E, Fritsche-Guenther R, Meisig J, Landthaler M, et al.
Mol Syst Biol
. 2017 May;
13(5):928.
PMID: 28468958
The RAF-MEK-ERK signalling pathway controls fundamental, often opposing cellular processes such as proliferation and apoptosis. Signal duration has been identified to play a decisive role in these cell fate decisions....
9.
Shinde V, Srinivasan S, Henry M, Rotshteyn T, Hescheler J, Rahnenfuhrer J, et al.
Stem Cell Res Ther
. 2017 Jan;
7(1):190.
PMID: 28038682
Background: Human embryonic stem cells (hESCs) partially recapitulate early embryonic three germ layer development, allowing testing of potential teratogenic hazards. Because use of hESCs is ethically debated, we investigated the...
10.
Shinde V, Hoelting L, Srinivasan S, Meisig J, Meganathan K, Jagtap S, et al.
Arch Toxicol
. 2016 May;
91(2):839-864.
PMID: 27188386
Stem cell-based in vitro test systems can recapitulate specific phases of human development. In the UKK test system, human pluripotent stem cells (hPSCs) randomly differentiate into cells of the three...