Johanna Roostalu
Overview
Explore the profile of Johanna Roostalu including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
18
Citations
878
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Real-Time Imaging of Single γTuRC-Mediated Microtubule Nucleation Events In Vitro by TIRF Microscopy
Consolati T, Henkin G, Roostalu J, Surrey T
Methods Mol Biol
. 2022 Apr;
2430:315-336.
PMID: 35476342
The γ-tubulin ring complex (γTuRC) is the major microtubule nucleator in cells. How γTuRC nucleates microtubules, and how nucleation is regulated is not understood. To gain an understanding of γTuRC...
2.
LaFrance B, Roostalu J, Henkin G, Greber B, Zhang R, Normanno D, et al.
Proc Natl Acad Sci U S A
. 2022 Jan;
119(2).
PMID: 34996871
Microtubules (MTs) are polymers of αβ-tubulin heterodimers that stochastically switch between growth and shrinkage phases. This dynamic instability is critically important for MT function. It is believed that GTP hydrolysis...
3.
Consolati T, Locke J, Roostalu J, Chen Z, Gannon J, Asthana J, et al.
Dev Cell
. 2020 May;
53(5):603-617.e8.
PMID: 32433913
The γ-tubulin ring complex (γTuRC) is the major microtubule nucleator in cells. The mechanism of its regulation is not understood. We purified human γTuRC and measured its nucleation properties in...
4.
Roostalu J, Thomas C, Cade N, Kunzelmann S, Taylor I, Surrey T
Elife
. 2020 Feb;
9.
PMID: 32053491
Microtubules are cytoskeletal polymers whose function depends on their property to switch between states of growth and shrinkage. Growing microtubules are thought to be stabilized by a GTP cap at...
5.
Roostalu J, Rickman J, Thomas C, Nedelec F, Surrey T
Cell
. 2018 Oct;
175(3):796-808.e14.
PMID: 30340043
During cell division, mitotic motors organize microtubules in the bipolar spindle into either polar arrays at the spindle poles or a "nematic" network of aligned microtubules at the spindle center....
6.
Zhang R, Roostalu J, Surrey T, Nogales E
Elife
. 2017 Nov;
6.
PMID: 29120325
During mitosis and meiosis, microtubule (MT) assembly is locally upregulated by the chromatin-dependent Ran-GTP pathway. One of its key targets is the MT-associated spindle assembly factor TPX2. The molecular mechanism...
7.
Fallesen T, Roostalu J, Duellberg C, Pruessner G, Surrey T
Biophys J
. 2017 Nov;
113(9):2055-2067.
PMID: 29117528
Most kinesin motors move in only one direction along microtubules. Members of the kinesin-5 subfamily were initially described as unidirectional plus-end-directed motors and shown to produce piconewton forces. However, some...
8.
Jha R, Roostalu J, Cade N, Trokter M, Surrey T
EMBO J
. 2017 Oct;
36(22):3387-3404.
PMID: 29038173
Cytoplasmic dynein is involved in a multitude of essential cellular functions. Dynein's activity is controlled by the combinatorial action of several regulatory proteins. The molecular mechanism of this regulation is...
9.
Roostalu J, Surrey T
Nat Rev Mol Cell Biol
. 2017 Aug;
18(11):702-710.
PMID: 28831203
Microtubules are cytoskeletal filaments central to a wide range of essential cellular functions in eukaryotic cells. Consequently, cells need to exert tight control over when, where and how many microtubules...
10.
Roostalu J, Cade N, Surrey T
Nat Cell Biol
. 2015 Oct;
17(11):1512.
PMID: 26515019
No abstract available.