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Johanna Roostalu

Explore the profile of Johanna Roostalu including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 878
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Recent Articles
11.
Roostalu J, Cade N, Surrey T
Nat Cell Biol . 2015 Sep; 17(11):1422-34. PMID: 26414402
Spindle assembly and function require precise control of microtubule nucleation and dynamics. The chromatin-driven spindle assembly pathway exerts such control locally in the vicinity of chromosomes. One of the key...
12.
Roostalu J, Surrey T
Nat Cell Biol . 2013 Aug; 15(8):889-91. PMID: 23907192
Multiple activities cooperate to determine the architecture of the mitotic spindle. Kip3 is a kinesin-8 motor protein in budding yeast that acts as a microtubule depolymerase. Now Kip3 is shown...
13.
Duellberg C, Fourniol F, Maurer S, Roostalu J, Surrey T
Trends Cell Biol . 2012 Oct; 23(2):54-63. PMID: 23103209
The microtubule cytoskeleton is crucial for the intracellular organization of eukaryotic cells. It is a dynamic scaffold that has to perform a variety of very different functions. This multitasking is...
14.
Roostalu J, Hentrich C, Bieling P, Telley I, Schiebel E, Surrey T
Science . 2011 Feb; 332(6025):94-9. PMID: 21350123
Kinesin motor proteins are thought to move exclusively in either one or the other direction along microtubules. Proteins of the kinesin-5 family are tetrameric microtubule cross-linking motors important for cell...
15.
Roostalu J, Schiebel E, Khmelinskii A
Cell Cycle . 2010 Apr; 9(6):1084-90. PMID: 20410686
Different organisms employ a variety of strategies to segregate their chromosomes during mitosis. Despite these differences, however, the basic regulatory principles that govern this intricate process are evolutionarily conserved. Above...
16.
Khmelinskii A, Roostalu J, Roque H, Antony C, Schiebel E
Dev Cell . 2009 Aug; 17(2):244-56. PMID: 19686685
The metaphase-to-anaphase transition is one of the most dramatic and highly regulated steps in cell division. At anaphase onset the protease separase dissolves sister chromatid cohesion. Simultaneously, the mitotic spindle...
17.
Roostalu J, Joers A, Luidalepp H, Kaldalu N, Tenson T
BMC Microbiol . 2008 Apr; 8:68. PMID: 18430255
Background: A fundamental characteristic of cells is the ability to divide. To date, most parameters of bacterial cultures, including cell division, have been measured as cell population averages, assuming that...
18.
Khmelinskii A, Lawrence C, Roostalu J, Schiebel E
J Cell Biol . 2007 Jun; 177(6):981-93. PMID: 17562791
Spindle elongation in anaphase of mitosis is a cell cycle-regulated process that requires coordination between polymerization, cross-linking, and sliding of microtubules (MTs). Proteins that assemble at the spindle midzone may...