Eva Nogales
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Explore the profile of Eva Nogales including associated specialties, affiliations and a list of published articles.
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205
Citations
11633
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Recent Articles
1.
Ariza A, Lue N, Grob P, Kaeser B, Fang J, Kassube S, et al.
bioRxiv
. 2025 Feb;
PMID: 39975028
Transcription and its regulation pose a major challenge for genome stability. The helicase RECQL5 has been proposed as an important factor to help safeguard the genome, and is the only...
2.
Ngo W, Peukes J, Baldwin A, Xue Z, Hwang S, Stickels R, et al.
Proc Natl Acad Sci U S A
. 2025 Jan;
122(1):e2413519121.
PMID: 39793042
The widespread application of genome editing to treat and cure disease requires the delivery of genome editors into the nucleus of target cells. Enveloped delivery vehicles (EDVs) are engineered virally...
3.
Cookis T, Lydecker A, Sauer P, Kasinath V, Nogales E
Nat Struct Mol Biol
. 2025 Jan;
32(2):393-404.
PMID: 39774834
Polycomb repressive complex 2 (PRC2) trimethylates histone H3 on K27 (H3K27me3) leading to gene silencing that is essential for embryonic development and maintenance of cell identity. PRC2 is regulated by...
4.
Liu H, Khera R, Grob P, Gallaher S, Purvine S, Nicora C, et al.
bioRxiv
. 2024 Dec;
PMID: 39713434
Iron (Fe) availability limits photosynthesis at a global scale where Fe-rich photosystem (PS) I abundance is drastically reduced in Fe-poor environments. We used single-particle cryo-electron microscopy to reveal a unique...
5.
Thawani A, Rodriguez-Vargas A, Van Treeck B, Hassan N, Adelson D, Nogales E, et al.
bioRxiv
. 2024 Nov;
PMID: 39605677
R2 retrotransposons are model site-specific eukaryotic non-LTR retrotransposons that copy-and-paste into gene loci encoding ribosomal RNAs. Recently we demonstrated that avian A-clade R2 proteins achieve efficient and precise insertion of...
6.
Perez-Bertoldi J, Zhao Y, Thawani A, Yildiz A, Nogales E
Nat Commun
. 2024 Nov;
15(1):9687.
PMID: 39516196
During mitosis, microtubule dynamics are regulated to ensure proper alignment and segregation of chromosomes. The dynamics of kinetochore-attached microtubules are regulated by hepatoma-upregulated protein (HURP) and the mitotic kinesin-8 Kif18A,...
7.
Sauer P, Pavlenko E, Cookis T, Zirden L, Renn J, Singhal A, et al.
Mol Cell
. 2024 Sep;
84(20):3885-3898.e8.
PMID: 39303719
Polycomb repressive complex 2 (PRC2) is an epigenetic regulator that trimethylates lysine 27 of histone 3 (H3K27me3) and is essential for embryonic development and cellular differentiation. H3K27me3 is associated with...
8.
Liu F, Yang Z, Wang C, You Z, Martin R, Qiao W, et al.
Cell
. 2024 Aug;
187(18):4877-4889.e15.
PMID: 39094568
Innate immune responses to microbial pathogens are regulated by intracellular receptors known as nucleotide-binding leucine-rich repeat receptors (NLRs) in both the plant and animal kingdoms. Across plant innate immune systems,...
9.
Ngo W, Peukes J, Baldwin A, Xue Z, Hwang S, Stickels R, et al.
bioRxiv
. 2024 Aug;
PMID: 39091760
The widespread application of genome editing to treat or even cure disease requires the delivery of genome editors into the nucleus of target cells. Enveloped Delivery Vehicles (EDVs) are engineered...
10.
Yang Z, Mameri A, Cattoglio C, Lachance C, Ariza A, Luo J, et al.
Science
. 2024 Aug;
385(6711):eadl5816.
PMID: 39088653
The human nucleosome acetyltransferase of histone H4 (NuA4)/Tat-interactive protein, 60 kilodalton (TIP60) coactivator complex, a fusion of the yeast switch/sucrose nonfermentable related 1 (SWR1) and NuA4 complexes, both incorporates the...