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Joel J Bruegger

Explore the profile of Joel J Bruegger including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 137
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Recent Articles
1.
Kahn-Kirby A, Amagata A, Maeder C, Mei J, Sideris S, Kosaka Y, et al.
PLoS One . 2019 Mar; 14(3):e0214250. PMID: 30921410
Background: Mitochondrial disease is a family of genetic disorders characterized by defects in the generation and regulation of energy. Epilepsy is a common symptom of mitochondrial disease, and in the...
2.
Hinman A, Holst C, Latham J, Bruegger J, Ulas G, McCusker K, et al.
PLoS One . 2018 Aug; 13(8):e0201369. PMID: 30110365
Ferroptosis is a form of programmed cell death associated with inflammation, neurodegeneration, and ischemia. Vitamin E (alpha-tocopherol) has been reported to prevent ferroptosis, but the mechanism by which this occurs...
3.
Hespen C, Bruegger J, Guo Y, Marletta M
ACS Chem Biol . 2018 May; 13(6):1631-1639. PMID: 29757599
Heme nitric oxide/oxygen sensing (H-NOX) domains are direct NO sensors that regulate a variety of biological functions in both bacteria and eukaryotes. Previous work on H-NOX proteins has shown that...
4.
Bruegger J, Smith B, Wynia-Smith S, Marletta M
J Biol Chem . 2018 Feb; 293(17):6282-6296. PMID: 29483187
Cysteine -nitrosation is a reversible post-translational modification mediated by nitric oxide (NO)-derived agents. -Nitrosation participates in cellular signaling and is associated with several diseases such as cancer, cardiovascular diseases, and...
5.
Hespen C, Bruegger J, Phillips-Piro C, Marletta M
ACS Chem Biol . 2016 Jun; 11(8):2337-46. PMID: 27328180
Acute and specific sensing of diatomic gas molecules is an essential facet of biological signaling. Heme nitric oxide/oxygen binding (H-NOX) proteins are a family of gas sensors found in diverse...