Michael A Marletta
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Explore the profile of Michael A Marletta including associated specialties, affiliations and a list of published articles.
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151
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5536
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Recent Articles
1.
Sayler R, Thomas W, Rose A, Marletta M
Proc Natl Acad Sci U S A
. 2025 Jan;
122(1):e2411229121.
PMID: 39793048
Polysaccharide monooxygenase (PMO) catalysis involves the chemically difficult hydroxylation of unactivated C-H bonds in carbohydrates. The reaction requires reducing equivalents and will utilize either oxygen or hydrogen peroxide as a...
2.
Batka A, Thomas W, Tudorica D, Sayler R, Marletta M
Biochemistry
. 2024 Nov;
63(23):3136-3146.
PMID: 39563485
Fungal polysaccharide monooxygenases (PMOs) oxidatively degrade cellulose and other carbohydrate polymers via a mononuclear copper active site using either O or HO as a cosubstrate. Cellulose-active fungal PMOs in the...
3.
Detomasi T, Batka A, Valastyan J, Hydorn M, Craik C, Bassler B, et al.
J Biol Chem
. 2023 Oct;
299(12):105386.
PMID: 37898401
Aggregation behavior provides bacteria protection from harsh environments and threats to survival. Two uncharacterized proteases, LapX and Lap, are important for Vibrio cholerae liquid-based aggregation. Here, we determined that LapX...
4.
Wittenborn E, Thomas W, Houghton K, Wirachman E, Wu Y, Marletta M
Biochemistry
. 2023 May;
62(10):1568-1576.
PMID: 37129924
Soluble guanylate cyclase (sGC) is the primary nitric oxide (NO) receptor in higher eukaryotes, including humans. NO-dependent signaling via sGC is associated with important physiological effects in the vascular, pulmonary,...
5.
Martinez-DAlto A, Yan X, Detomasi T, Sayler R, Thomas W, Talbot N, et al.
Proc Natl Acad Sci U S A
. 2023 Feb;
120(8):e2215426120.
PMID: 36791100
Blast disease in cereal plants is caused by the fungus and accounts for a significant loss in food crops. At the outset of infection, expression of a putative polysaccharide monooxygenase...
6.
Detomasi T, Rico-Ramirez A, Sayler R, Goncalves A, Marletta M, Glass N
Elife
. 2022 Aug;
11.
PMID: 36040303
Organisms require the ability to differentiate themselves from organisms of different or even the same species. Allorecognition processes in filamentous fungi are essential to ensure identity of an interconnected syncytial...
7.
Lemon C, Hanley D, Batka A, Marletta M
Inorg Chem
. 2022 Jun;
61(27):10521-10532.
PMID: 35766625
Ratiometric sensors are self-referencing constructs that are functional in cells and tissues, and the read-out is independent of sensor concentration. One strategy for ratiometric sensing is to utilize two-color emission,...
8.
Lemon C, Nissley A, Latorraca N, Wittenborn E, Marletta M
RSC Chem Biol
. 2022 Jun;
3(5):571-581.
PMID: 35656484
Replacing the native porphyrin cofactor in haem proteins has led to the development of novel designer proteins for a variety of applications. In most cases, haem analogues bind in a...
9.
Reyes-Rivera J, Wu Y, Guthrie B, Marletta M, King N, Brunet T
Curr Biol
. 2022 May;
32(11):2539-2547.e5.
PMID: 35504284
Although signaling by the gaseous molecule nitric oxide (NO) regulates key physiological processes in animals, including contractility, immunity, development, and locomotion, the early evolution of animal NO signaling remains unclear....
10.
Mitchell G, Silvis M, Talkington K, Budzik J, Dodd C, Paluba J, et al.
mBio
. 2022 Jan;
13(1):e0272621.
PMID: 35073755
Ceragenins are a family of synthetic amphipathic molecules designed to mimic the properties of naturally occurring cationic antimicrobial peptides (CAMPs). Although ceragenins have potent antimicrobial activity, whether their mode of...