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Joel F Habener

Explore the profile of Joel F Habener including associated specialties, affiliations and a list of published articles. Areas
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Articles 56
Citations 1790
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Recent Articles
1.
Drucker D, Habener J, Holst J
J Clin Invest . 2017 Dec; 127(12):4217-4227. PMID: 29202475
The discovery, characterization, and clinical development of glucagon-like-peptide-1 (GLP-1) spans more than 30 years and includes contributions from multiple investigators, science recognized by the 2017 Harrington Award Prize for Innovation...
2.
Habener J, Stanojevic V
Cell Metab . 2017 Apr; 25(4):757-758. PMID: 28380367
The gut is believed to be the source of GLP-1 that augments insulin secretion in response to oral nutrients. In this issue of Cell Metabolism, Chambers et al. (2017) shift...
3.
Stanojevic V, Habener J
Best Pract Res Clin Endocrinol Metab . 2015 Dec; 29(6):859-71. PMID: 26696515
The alpha cells that co-occupy the islets in association with beta cells have been long recognized as the source of glucagon, a hyperglycemia-producing and diabetogenic hormone. Although the mechanisms that...
4.
Elahi D, Ruff D, Carlson O, Meneilly G, Habener J, Egan J
Endocr Res . 2015 Jul; 41(1):16-20. PMID: 26186406
Purpose/aim: Negative feedback controls in endocrine regulatory systems are well recognized. The incretins and their role in glucose regulation have been of major interest recently. Whether the same negative control...
5.
Tomas E, Stanojevic V, McManus K, Khatri A, Everill P, Bachovchin W, et al.
Diabetes . 2015 Apr; 64(7):2409-19. PMID: 25858562
The prevalence of obesity-related diabetes is increasing worldwide. Here we report the identification of a pentapeptide, GLP-1(32-36)amide (LVKGRamide), derived from the glucoincretin hormone GLP-1, that increases basal energy expenditure and...
6.
Elahi D, Angeli F, Vakilipour A, Carlson O, Tomas E, Egan J, et al.
Peptides . 2014 Jun; 59:20-4. PMID: 24937653
We have previously demonstrated in human subjects who under euglycemic clamp conditions GLP-1(9-36)amide infusions inhibit endogenous glucose production without substantial insulinotropic effects. An earlier report indicates that GLP-1(9-36)amide is cleaved...
7.
Unger R, Berglund E, Habener J, Cherrington A
Nat Med . 2013 Mar; 19(3):272-3. PMID: 23467236
No abstract available.
8.
Habener J, Stanojevic V
Trends Endocrinol Metab . 2012 Dec; 24(3):153-63. PMID: 23260869
The alpha cells that coinhabit the islets with the insulin-producing beta cells have recently captured the attention of diabetes researchers because of new breakthrough findings highlighting the importance of these...
9.
Habener J, Stanojevic V
Islets . 2012 Aug; 4(3):188-98. PMID: 22847495
This review considers the role of α-cells in β-cell generation and regeneration. We present recent evidence obtained from lineage-tracing studies showing that α-cells can serve as progenitors of β-cells and...
10.
Liu Z, Stanojevic V, Brindamour L, Habener J
J Endocrinol . 2012 Mar; 213(2):143-54. PMID: 22414687
Type 2 diabetes, often associated with obesity, results from a deficiency of insulin production and action manifested in increased blood levels of glucose and lipids that further promote insulin resistance...