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Jochen K Lennerz

Explore the profile of Jochen K Lennerz including associated specialties, affiliations and a list of published articles. Areas
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Articles 215
Citations 6924
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Recent Articles
1.
Baumgart D, Schneider N, Lauterbach K, Lennerz J
Lancet . 2025 Mar; 405(10482):890-891. PMID: 40089368
No abstract available.
2.
Turova P, Kushnarev V, Baranov O, Butusova A, Menshikova S, Yong S, et al.
NPJ Breast Cancer . 2025 Feb; 11(1):19. PMID: 39979291
Current breast cancer classification methods, particularly immunohistochemistry and PAM50, face challenges in accurately characterizing the HER2-low subtype, a therapeutically relevant entity with distinct biological features. This notable gap can lead...
3.
Lau M, Borowsky J, Vayrynen J, Haruki K, Zhao M, Dias Costa A, et al.
PLoS Comput Biol . 2025 Feb; 21(2):e1012707. PMID: 39965007
Background: Growing evidence supports the importance of characterizing the organizational patterns of various cellular constituents in the tumor microenvironment in precision oncology. Most existing data on immune cell infiltrates in...
4.
Blohmer M, Cheek D, Hung W, Kessler M, Chatzidimitriou F, Wang J, et al.
Nat Genet . 2025 Feb; 57(3):706-717. PMID: 39905260
Cell division drives somatic evolution but is challenging to quantify. We developed a framework to count cell divisions with DNA replication-related mutations in polyguanine homopolymers. Analyzing 505 samples from 37...
5.
Rabe D, Choudhury A, Lee D, Luciani E, Ho U, Clark A, et al.
Sci Adv . 2025 Jan; 11(2):eadh1167. PMID: 39792670
Measuring virus in biofluids is complicated by confounding biomolecules coisolated with viral nucleic acids. To address this, we developed an affinity-based microfluidic device for specific capture of intact severe acute...
6.
Kaj-Carbaidwala B, Fevery J, Adler D, Bergquist A, de Ridder L, Deneau M, et al.
J Pediatr Gastroenterol Nutr . 2024 Dec; 80(3):450-454. PMID: 39704261
Primary sclerosing cholangitis (PSC) is a risk factor for cholangiocarcinoma. When a child is diagnosed with both PSC and inflammatory bowel disease (IBD), evidence-based information on counseling families and risk...
7.
Fisch A, Farahani A, Thierauf J, Iafrate A, Lennerz J, Faquin W
Head Neck Pathol . 2024 Oct; 18(1):114. PMID: 39460831
Purpose: MYB has been shown to play a central role in oncogenesis in a majority of adenoid cystic carcinomas (ACC). Testing for MYB expression via immunohistochemistry (IHC) or testing for...
8.
Burr R, Leshchiner I, Costantino C, Blohmer M, Sundaresan T, Cha J, et al.
Nat Cancer . 2024 Oct; 5(11):1681-1696. PMID: 39406916
Although the development of multiple primary tumors in smokers with lung cancer can be attributed to carcinogen-induced field cancerization, the occurrence of multiple tumors at presentation in individuals with EGFR-mutant...
9.
Wassenaar E, Gorelick A, Hung W, Cheek D, Kucukkose E, Lee I, et al.
bioRxiv . 2024 Oct; PMID: 39386634
Whether metastasis in humans can be accomplished by most primary tumor cells or requires the evolution of a specialized trait remains an open question. To evaluate whether metastases are founded...
10.
Jackson B, Rashidi H, Lennerz J, de Baca M
Arch Pathol Lab Med . 2024 Sep; 149(2):123-129. PMID: 39299704
Context.—: Technology companies and research groups are increasingly exploring applications of generative artificial intelligence (GenAI) in pathology and laboratory medicine. Although GenAI holds considerable promise, it also introduces novel risks...