Joanna Groden
Overview
Explore the profile of Joanna Groden including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
54
Citations
2076
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
McIlhatton M, Boivin G, Groden J
Biomed Res Int
. 2016 Jul;
2016:1414383.
PMID: 27413734
Technical and biological innovations have enabled the development of more sophisticated and focused murine models that increasingly recapitulate the complex pathologies of human diseases, in particular cancer. Mouse models provide...
12.
McIlhatton M, Murnan K, Carson D, Boivin G, Croce C, Groden J
Cancer Prev Res (Phila)
. 2015 Apr;
8(7):650-6.
PMID: 25908507
Although disruption of DNA repair capacity is unquestionably associated with cancer susceptibility in humans and model organisms, it remains unclear if the inherent tumor phenotypes of DNA repair deficiency syndromes...
13.
Acharya S, Kaul Z, Gocha A, Martinez A, Harris J, Parvin J, et al.
PLoS One
. 2014 Aug;
9(8):e103819.
PMID: 25084169
Fifteen percent of tumors utilize recombination-based alternative lengthening of telomeres (ALT) to maintain telomeres. The mechanisms underlying ALT are unclear but involve several proteins involved in homologous recombination including the...
14.
Valeri N, Braconi C, Gasparini P, Murgia C, Lampis A, Paulus-Hock V, et al.
Cancer Cell
. 2014 Apr;
25(4):469-83.
PMID: 24735923
MicroRNA deregulation is frequent in human colorectal cancers (CRCs), but little is known as to whether it represents a bystander event or actually drives tumor progression in vivo. We show...
15.
Gocha A, Acharya S, Groden J
PLoS One
. 2014 Apr;
9(4):e93991.
PMID: 24709898
Telomere maintenance can occur in the presence of telomerase or in its absence, termed alternative lengthening of telomeres (ALT). ALT adds telomere repeats using recombination-based processes and DNA repair proteins...
16.
Amunugama R, Groden J, Fishel R
DNA Repair (Amst)
. 2013 Jul;
12(9):723-32.
PMID: 23810717
There are six human RAD51 related proteins (HsRAD51 paralogs), HsRAD51B, HsRAD51C, HsRAD51D, HsXRCC2, HsXRCC3 and HsDMC1, that appear to enhance HsRAD51 mediated homologous recombinational (HR) repair of DNA double strand...
17.
Perchiniak E, Groden J
Curr Colorectal Cancer Rep
. 2013 Jan;
7(2):145-151.
PMID: 23308069
Colorectal cancer (CRC) results from the progressive accumulation of both genetic and epigenetic alterations that lead to the transformation of normal colorectal epithelium to benign (adenoma) and invasive (carcinoma) disease....
18.
Grierson P, Acharya S, Groden J
Mutat Res
. 2012 Dec;
743-744:89-96.
PMID: 23261817
Bloom's syndrome (BS) is an inherited disorder caused by loss of function of the recQ-like BLM helicase. It is characterized clinically by severe growth retardation and cancer predisposition. BLM localizes...
19.
Gocha A, Nuovo G, Iwenofu O, Groden J
Am J Pathol
. 2012 Dec;
182(1):41-8.
PMID: 23260199
Telomere shortening necessitates that tumor cells activate a telomere maintenance mechanism (TMM) to support immortalization. Although most tumor cells activate expression of the enzyme telomerase, some cells elongate telomeres in...
20.
Gocha A, Harris J, Groden J
Mutat Res
. 2012 Dec;
743-744:142-150.
PMID: 23219603
Telomeres protect chromosome termini to maintain genomic stability and regulate cellular lifespan. Maintenance of telomere length is required for neoplastic cells after the acquisition of mutations that deregulate cell cycle...