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Jimmy R Theriault

Explore the profile of Jimmy R Theriault including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 623
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Recent Articles
1.
Wurst J, Drake E, Theriault J, Jewett I, VerPlank L, Perez J, et al.
ACS Chem Biol . 2014 May; 9(7):1536-44. PMID: 24824984
Pseudomonas aeruginosa produces the peptide siderophore pyoverdine, which is used to acquire essential Fe(3+) ions from the environment. PvdQ, an Ntn hydrolase, is required for the biosynthesis of pyoverdine. PvdQ...
2.
Adams D, Boskovic Z, Theriault J, Wang A, Stern A, Wagner B, et al.
ACS Chem Biol . 2013 Mar; 8(5):923-9. PMID: 23477340
Elevation of reactive oxygen species (ROS) levels has been observed in many cancer cells relative to nontransformed cells, and recent reports have suggested that small-molecule enhancers of ROS may selectively...
3.
Theriault J, Felts A, Bates B, Perez J, Palmer M, Gilbert S, et al.
Bioorg Med Chem Lett . 2011 Dec; 22(1):76-81. PMID: 22172704
Hypoxia and ischemia are linked to several serious public health problems that affect most major organ systems. Specific examples include diseases of the cardiovascular, pulmonary, renal, neurologic, and musculoskeletal systems....
4.
Theriault J, Palmer H, Pittman D
Biochem Biophys Res Commun . 2011 May; 409(3):500-5. PMID: 21600878
Metformin (Met), an AMP-activated protein kinase (AMPK) inducer, is primarily transported by organic cation transporters expressed at the surface of renal proximal tubular epithelial cells. However, the implication of Met...
5.
Calderwood S, Gong J, Theriault J, Mambula S, Gray Jr P
Novartis Found Symp . 2008 Jun; 291:115-31. PMID: 18575270
Heat shock proteins (HSPs) play important roles in the immune system as carriers of tumour antigens and inflammatory agents. The HSPs are abundantly expressed stress proteins intrinsic to all cellular...
6.
Calderwood S, Mambula S, Gray Jr P, Theriault J
FEBS Lett . 2007 May; 581(19):3689-94. PMID: 17499247
Extracellular stress proteins including heat shock proteins (Hsp) and glucose regulated proteins (Grp) are emerging as important mediators of intercellular signaling and transport. Release of such proteins from cells is...
7.
Theriault J, Adachi H, Calderwood S
J Immunol . 2006 Dec; 177(12):8604-11. PMID: 17142759
Extracellular heat shock protein 70 (Hsp70) exerts profound effects both in mediating tumor rejection by Hsp70-based vaccines and in autoimmunity. Further progress in this area, however, awaits the identification of...
8.
Calderwood S, Theriault J, Gong J
Int J Hyperthermia . 2005 Dec; 21(8):713-6. PMID: 16338853
There is growing body of evidence linking the cellular response to heat stress with the response of the immune system to cancer. The anti-tumor immune response can be markedly enhanced...
9.
Calderwood S, Theriault J, Gong J
Eur J Immunol . 2005 Sep; 35(9):2518-27. PMID: 16144035
Extracellular heat shock protein 70 (HSP70) is a potent agent for tumor immunotherapy, which can break tolerance to tumor-associated antigens and cause specific tumor cell killing by cytotoxic CD8+ T...
10.
Chavez Zobel A, Lambert H, Theriault J, Landry J
Cell Stress Chaperones . 2005 Jul; 10(2):157-66. PMID: 16038412
Mutations in the alpha-crystallin domain of 4 of the small heat shock proteins (sHsp) (Hsp27/HspB1, alphaA-crystallin/ HspB4, alphaB-crystallin/HspB5, and HspB8) are responsible for dominant inherited diseases in humans. One such...