Jimmy Phan
Overview
Explore the profile of Jimmy Phan including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
275
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0
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Recent Articles
1.
Soni N, Hohsfield L, Tran K, Kawauchi S, Walker A, Javonillo D, et al.
Alzheimers Dement
. 2024 Mar;
20(4):2794-2816.
PMID: 38426371
Introduction: Alzheimer's disease (AD) is a neurodegenerative disorder with multifactorial etiology, including genetic factors that play a significant role in disease risk and resilience. However, the role of genetic diversity...
2.
Tran K, Kawauchi S, Kramar E, Rezaie N, Liang H, Sakr J, et al.
Mol Neurodegener
. 2023 Feb;
18(1):12.
PMID: 36803190
Background: The TREM2 R47H variant is one of the strongest genetic risk factors for late-onset Alzheimer's Disease (AD). Unfortunately, many current Trem2 mouse models are associated with cryptic mRNA splicing...
3.
Dinh H, Phan J, Lountzis N, Purcell S
Cutis
. 2022 Feb;
108(6):342-344.
PMID: 35167789
Nephrogenic systemic fibrosis (NSF) is a rare disease that can present in patients with kidney injury who have been exposed to gadolinium-based contrast agents (GBCAs). These patients can easily be...
4.
Javonillo D, Tran K, Phan J, Hingco E, Kramar E, Da Cunha C, et al.
Front Neurosci
. 2022 Feb;
15:785276.
PMID: 35140584
Animal models of disease are valuable resources for investigating pathogenic mechanisms and potential therapeutic interventions. However, for complex disorders such as Alzheimer's disease (AD), the generation and availability of innumerous...
5.
Forner S, Kawauchi S, Balderrama-Gutierrez G, Kramar E, Matheos D, Phan J, et al.
Sci Data
. 2021 Oct;
8(1):270.
PMID: 34654824
Mouse models of human diseases are invaluable tools for studying pathogenic mechanisms and testing interventions and therapeutics. For disorders such as Alzheimer's disease in which numerous models are being generated,...
6.
Baglietto-Vargas D, Forner S, Cai L, Martini A, Trujillo-Estrada L, Swarup V, et al.
Nat Commun
. 2021 Apr;
12(1):2421.
PMID: 33893290
The majority of Alzheimer's disease (AD) cases are late-onset and occur sporadically, however most mouse models of the disease harbor pathogenic mutations, rendering them better representations of familial autosomal-dominant forms...
7.
Forner S, Martini A, Prieto G, Dang C, Rodriguez-Ortiz C, Reyes-Ruiz J, et al.
Sci Rep
. 2019 Nov;
9(1):15936.
PMID: 31685865
Alzheimer's disease (AD), the most common age-related neurodegenerative disorder, is currently conceptualized as a disease of synaptic failure. Synaptic impairments are robust within the AD brain and better correlate with...
8.
Martini A, Gomez-Arboledas A, Forner S, Rodriguez-Ortiz C, McQuade A, Danhash E, et al.
Proc Natl Acad Sci U S A
. 2019 Oct;
116(42):21198-21206.
PMID: 31570577
Defects in interleukin-1β (IL-1β)-mediated cellular responses contribute to Alzheimer's disease (AD). To decipher the mechanism associated with its pathogenesis, we investigated the molecular events associated with the termination of IL-1β...