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Jimena Andersen

Explore the profile of Jimena Andersen including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 2013
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Recent Articles
1.
Kim J, Miura Y, Li M, Revah O, Selvaraj S, Birey F, et al.
Neuron . 2024 Oct; 112(24):4048-4059.e7. PMID: 39419023
Abnormalities in thalamocortical crosstalk can lead to neuropsychiatric disorders. Variants in CACNA1G, which encodes the α1G subunit of the thalamus-enriched T-type calcium channel, are associated with absence seizures, intellectual disability,...
2.
Pio T, Hill E, Kebede N, Andersen J, Sloan S
Adv Neurobiol . 2024 Aug; 39:69-93. PMID: 39190072
This chapter explores the intricate interactions between neurons and astrocytes within the nervous system with a particular emphasis on studies conducted in human tissue or with human cells. We specifically...
3.
Andersen J, Thom N, Shadrach J, Chen X, Onesto M, Amin N, et al.
Nat Neurosci . 2023 Apr; 26(5):902-914. PMID: 37095394
Understanding spinal cord assembly is essential to elucidate how motor behavior is controlled and how disorders arise. The human spinal cord is exquisitely organized, and this complex organization contributes to...
4.
Revah O, Gore F, Kelley K, Andersen J, Sakai N, Chen X, et al.
Nature . 2022 Oct; 610(7931):319-326. PMID: 36224417
Self-organizing neural organoids represent a promising in vitro platform with which to model human development and disease. However, organoids lack the connectivity that exists in vivo, which limits maturation and...
5.
Trevino A, Muller F, Andersen J, Sundaram L, Kathiria A, Shcherbina A, et al.
Cell . 2021 Aug; 184(19):5053-5069.e23. PMID: 34390642
Genetic perturbations of cortical development can lead to neurodevelopmental disease, including autism spectrum disorder (ASD). To identify genomic regions crucial to corticogenesis, we mapped the activity of gene-regulatory elements generating...
6.
Gordon A, Yoon S, Tran S, Makinson C, Park J, Andersen J, et al.
Nat Neurosci . 2021 Feb; 24(3):331-342. PMID: 33619405
Human stem-cell-derived models provide the promise of accelerating our understanding of brain disorders, but not knowing whether they possess the ability to mature beyond mid- to late-fetal stages potentially limits...
7.
Andersen J, Revah O, Miura Y, Thom N, Amin N, Kelley K, et al.
Cell . 2020 Dec; 183(7):1913-1929.e26. PMID: 33333020
Neurons in the cerebral cortex connect through descending pathways to hindbrain and spinal cord to activate muscle and generate movement. Although components of this pathway have been previously generated and...
8.
Trevino A, Sinnott-Armstrong N, Andersen J, Yoon S, Huber N, Pritchard J, et al.
Science . 2020 Jan; 367(6476). PMID: 31974223
Forebrain development is characterized by highly synchronized cellular processes, which, if perturbed, can cause disease. To chart the regulatory activity underlying these events, we generated a map of accessible chromatin...
9.
Andersen J, Pasca S
Nature . 2018 Oct; 563(7729):44-45. PMID: 30375499
No abstract available.
10.
Sloan S, Andersen J, Pasca A, Birey F, Pasca S
Nat Protoc . 2018 Sep; 13(9):2062-2085. PMID: 30202107
The ability to generate region-specific three-dimensional (3D) models to study human brain development offers great promise for understanding the nervous system in both healthy individuals and patients. In this protocol,...