Jillian N Pearring
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Explore the profile of Jillian N Pearring including associated specialties, affiliations and a list of published articles.
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23
Citations
741
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Recent Articles
1.
Martinez-Marquez J, Hua S, Beu A, Stein C, Pearring J
bioRxiv
. 2025 Jan;
PMID: 39764054
Vertebrate vision in dim-light environments is initiated by rod photoreceptor cells that express the photopigment rhodopsin, a G-protein coupled receptor (GPCR). To ensure efficient light capture, rhodopsin is densely packed...
2.
Abdel-Salam G, Hellmuth S, Gradhand E, Kaseberg S, Winter J, Pabst A, et al.
JCI Insight
. 2023 Oct;
8(22).
PMID: 37796616
MAD2L1BP-encoded p31comet mediates Trip13-dependent disassembly of Mad2- and Rev7-containing complexes and, through this antagonism, promotes timely spindle assembly checkpoint (SAC) silencing, faithful chromosome segregation, insulin signaling, and homology-directed repair (HDR)...
3.
Truong H, Cruz-Colon K, Martinez-Marquez J, Willer J, Travis A, Biswas S, et al.
Nat Commun
. 2023 Sep;
14(1):5671.
PMID: 37704658
The primary cilium is a signaling organelle with a unique membrane composition maintained by a diffusional barrier residing at the transition zone. Many transition zone proteins, such as the tectonic...
4.
Travis A, Pearring J
Adv Exp Med Biol
. 2023 Jul;
1415:283-288.
PMID: 37440046
Photoreceptors are highly polarized sensory neurons. Precise localization of signaling molecules within the ciliary outer segment is critical for photoreceptor function and viability. The small GTPase Arl3 plays a particularly...
5.
Thorson M, Wei S, Johnson C, Gabriel C, Arshavsky V, Pearring J
Front Mol Neurosci
. 2023 May;
16:1161127.
PMID: 37181654
Photoreceptors are sensory neurons that capture light within their outer segment, a narrow cylindrical organelle stacked with disc-shaped membranes housing the visual pigment. Photoreceptors are the most abundant neurons in...
6.
Nuzhat N, Van Schil K, Liakopoulos S, Bauwens M, Duenas Rey A, Kaseberg S, et al.
J Clin Invest
. 2023 Mar;
133(8).
PMID: 36862503
Defects in primary or motile cilia result in a variety of human pathologies, and retinal degeneration is frequently associated with these so-called ciliopathies. We found that homozygosity for a truncating...
7.
Hotta T, Plemmons A, Gebbie M, Ziehm T, Blasius T, Johnson C, et al.
Biomolecules
. 2023 Feb;
13(2).
PMID: 36830726
An important post-translational modification (PTM) of α-tubulin is the removal of amino acids from its C-terminus. Removal of the C-terminal tyrosine residue yields detyrosinated α-tubulin, and subsequent removal of the...
8.
Travis A, Manocha S, Willer J, Wessler T, Skiba N, Pearring J
Elife
. 2023 Jan;
12.
PMID: 36598133
The small GTPase Arl3 is important for the enrichment of lipidated proteins to primary cilia, including the outer segment of photoreceptors. Human mutations in the small GTPase Arl3 cause both...
9.
Pearring J, Martinez-Marquez J, Willer J, Lieu E, Salinas R, Arshavsky V
J Neurosci
. 2021 Feb;
41(14):3094-3104.
PMID: 33637563
Vision begins when light is captured by the outer segment organelle of photoreceptor cells in the retina. Outer segments are modified cilia filled with hundreds of flattened disk-shaped membranes. Disk...
10.
Spencer W, Lewis T, Pearring J, Arshavsky V
Trends Cell Biol
. 2020 Sep;
30(11):904-915.
PMID: 32900570
The light-sensitive outer segment organelle of the vertebrate photoreceptor cell is a modified cilium filled with hundreds of flattened 'disc' membranes that provide vast light-absorbing surfaces. The outer segment is...