Jiaowei Wang
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Explore the profile of Jiaowei Wang including associated specialties, affiliations and a list of published articles.
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10
Citations
88
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Recent Articles
1.
Wang J, Xie W, Li N, Li W, Zhang Z, Fan N, et al.
Cell Stem Cell
. 2023 Sep;
30(9):1235-1245.e6.
PMID: 37683604
Heterologous organ transplantation is an effective way of replacing organ function but is limited by severe organ shortage. Although generating human organs in other large mammals through embryo complementation would...
2.
Zhou J, Wang J, Chen F, Zhuang Z, Chen M, Yang Y, et al.
PLoS One
. 2023 Aug;
18(8):e0289509.
PMID: 37540669
Transcription activator-like effectors (TALEs) have been widely used for genome editing, transcriptional regulation, and locus-specific DNA imaging. However, TALEs are difficult to handle in routine laboratories because of their complexity...
3.
Chen F, Lian M, Ma B, Gou S, Luo X, Yang K, et al.
Commun Biol
. 2022 Nov;
5(1):1163.
PMID: 36323848
Cas12a can process multiple sgRNAs from a single transcript of CRISPR array, conferring advantages in multiplexed base editing when incorporated into base editor systems, which is extremely helpful given that...
4.
Li Y, Wang H, Chen H, Liao Y, Gou S, Yan Q, et al.
FASEB J
. 2022 Oct;
36(11):e22611.
PMID: 36250915
Obesity is among the strongest risk factors for type 2 diabetes (T2D). The CREBRF missense allele rs373863828 (p. Arg457Gln, p. R457Q) is associated with increased body mass index but reduced...
5.
Jin Q, Yang X, Gou S, Liu X, Zhuang Z, Liang Y, et al.
Sci China Life Sci
. 2022 May;
65(11):2269-2286.
PMID: 35596888
Inducible expression systems are indispensable for precise regulation and in-depth analysis of biological process. Binary Tet-On system has been widely employed to regulate transgenic expression by doxycycline. Previous pig models...
6.
Zhu Y, Zhang Z, Fan N, Huang K, Li H, Gu J, et al.
Stem Cell Reports
. 2022 Apr;
17(5):1059-1069.
PMID: 35427483
Obtaining functional human cells through interspecies chimerism with human pluripotent stem cells (hPSCs) remains unsuccessful due to its extremely low efficiency. Here, we show that hPSCs failed to differentiate and...
7.
Liu Y, Yang Y, Suo Y, Li C, Chen M, Zheng S, et al.
Mol Ther Methods Clin Dev
. 2022 Mar;
24:332-341.
PMID: 35229007
Pluripotent stem cells (PSCs) are promising in regenerative medicine. A major challenge of PSC therapy is the risk of teratoma formation because of the contamination of undifferentiated stem cells. Constitutive...
8.
Lian M, Chen F, Huang X, Zhao X, Gou S, Li N, et al.
J Genet Genomics
. 2021 Jan;
48(1):92-95.
PMID: 33504469
No abstract available.
9.
Li N, Gou S, Wang J, Zhang Q, Huang X, Xie J, et al.
Mol Ther
. 2020 Nov;
29(3):1001-1015.
PMID: 33221434
Patients with hereditary tyrosinemia type I (HT1) present acute and irreversible liver and kidney damage during infancy. CRISPR-Cas9-mediated gene correction during infancy may provide a promising approach to treat patients...
10.
Xie J, Huang X, Wang X, Gou S, Liang Y, Chen F, et al.
BMC Biol
. 2020 Sep;
18(1):131.
PMID: 32967664
Background: Many favorable traits of crops and livestock and human genetic diseases arise from multiple single nucleotide polymorphisms or multiple point mutations with heterogeneous base substitutions at the same locus....