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Jia-Hui Ng

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Articles 12
Citations 1099
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Recent Articles
1.
Kew Y, Tan C, Ng C, Thang S, Tan L, Khoo Y, et al.
Rheumatol Int . 2016 Dec; 37(4):633-639. PMID: 28013358
The prevalence of neuropathic low back pain differs in different ethnic populations. The aims of the study are to determine its frequency and associations in a multi-ethnic cohort of Asian...
2.
Yeo J, Jiang J, Tan Z, Yim G, Ng J, Goke J, et al.
Cell Stem Cell . 2014 Jun; 14(6):864-72. PMID: 24905170
The maintenance of mouse embryonic stem cells (mESCs) requires LIF and serum. However, a pluripotent "ground state," bearing resemblance to preimplantation mouse epiblasts, can be established through dual inhibition (2i)...
3.
Chan Y, Goke J, Ng J, Lu X, Gonzales K, Tan C, et al.
Cell Stem Cell . 2013 Dec; 13(6):663-75. PMID: 24315441
Human embryonic stem cells (hESCs) are derived from the inner cell mass of the blastocyst. Despite sharing the common property of pluripotency, hESCs are notably distinct from epiblast cells of...
4.
Ng J, Kumar V, Muratani M, Kraus P, Yeo J, Yaw L, et al.
Dev Cell . 2013 Jan; 24(3):324-33. PMID: 23352811
The limited number of in vivo germ cells poses an impediment to genome-wide studies. Here, we applied a small-scale chromatin immunoprecipitation sequencing (ChIP-seq) method on purified mouse fetal germ cells...
5.
Percharde M, Lavial F, Ng J, Kumar V, Tomaz R, Martin N, et al.
Genes Dev . 2012 Sep; 26(20):2286-98. PMID: 23019124
Embryonic stem cell (ESC) pluripotency depends on a well-characterized gene regulatory network centered on Oct4, Sox2, and Nanog. In contrast, little is known about the identity of the key coregulators...
6.
Xue K, Ng J, Ng H
Philos Trans R Soc Lond B Biol Sci . 2011 Jul; 366(1575):2238-46. PMID: 21727129
There has been an immense interest in embryonic stem cells owing to their pluripotent property, which refers to the ability to differentiate into all cell types of an embryo. In...
7.
Ng J, Ng H
Nat Genet . 2010 Nov; 42(12):1035-6. PMID: 21102618
No abstract available.
8.
Heng J, Feng B, Han J, Jiang J, Kraus P, Ng J, et al.
Cell Stem Cell . 2010 Jan; 6(2):167-74. PMID: 20096661
Somatic cells can be reprogrammed to induced pluripotent stem cells (iPSCs) with the introduction of Oct4, Sox2, Klf4, and c-Myc. Among these four factors, Oct4 is critical in inducing pluripotency...
9.
Feng B, Ng J, Heng J, Ng H
Cell Stem Cell . 2009 Apr; 4(4):301-12. PMID: 19341620
Reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) can be achieved by viral-mediated transduction of defined transcription factors. Moving toward the eventual goal of clinical application, it is...
10.
Feng B, Jiang J, Kraus P, Ng J, Heng J, Chan Y, et al.
Nat Cell Biol . 2009 Jan; 11(2):197-203. PMID: 19136965
The dominant effect of transcription factors in imparting expanded potency is best exemplified by the reprogramming of fibroblasts to pluripotent cells using retrovirus-mediated transduction of defined transcription factors. In the...