Yuin-Han Loh
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Explore the profile of Yuin-Han Loh including associated specialties, affiliations and a list of published articles.
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Articles
73
Citations
9278
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Recent Articles
1.
Liu H, Oh S, Tay N, Lim C, Hsu C, Chua D, et al.
Animals (Basel)
. 2025 Jan;
15(2.
PMID: 39858147
A time-lapse live embryo monitoring system provides a powerful approach to recording dynamic developmental events of cultured embryos in detail. By obtaining continuous short-interval images, blastocyst formation can be predicted...
2.
Wong K, Zeng Y, Tay E, Teo J, Cipta N, Hamashima K, et al.
Nat Commun
. 2024 Nov;
15(1):10011.
PMID: 39562549
Embryonic stem cells possess the remarkable ability to self-organize into blastocyst-like structures upon induction. These stem cell-based embryo models serve as invaluable platforms for studying embryogenesis and therapeutic developments. Nevertheless,...
3.
Kamaraj U, Gautam P, Cheng T, Chin T, Tay S, Ho T, et al.
bioRxiv
. 2024 Aug;
PMID: 39149248
Ovarian clear cell carcinoma (CCC) has an East Asian preponderance. It is associated with endometriosis, a benign condition where endometrial (inner lining of the uterus) tissue is found outside the...
4.
Chooi W, Winanto , Zeng Y, Lee C, Lim Z, Gautam P, et al.
Emerg Microbes Infect
. 2024 Jul;
13(1):2382235.
PMID: 39017655
Enterovirus A71 (EV-A71) causes Hand, Foot, and Mouth Disease and has been clinically associated with neurological complications. However, there is a lack of relevant models to elucidate the neuropathology of...
5.
Feng J, Chuah Y, Liang Y, Cipta N, Zeng Y, Warrier T, et al.
Nucleic Acids Res
. 2024 May;
52(12):7063-7080.
PMID: 38808662
Cohesin plays a crucial role in the organization of topologically-associated domains (TADs), which influence gene expression and DNA replication timing. Whether epigenetic regulators may affect TADs via cohesin to mediate...
6.
Bao Q, Tay N, Lim C, Chua D, Kee S, Choolani M, et al.
Sci Rep
. 2024 Jan;
14(1):2391.
PMID: 38287040
Advanced molecular and cellular technologies provide promising tools for wildlife and biodiversity conservation. Induced pluripotent stem cell (iPSC) technology offers an easily accessible and infinite source of pluripotent stem cells,...
7.
Ng M, Kwok I, Tan L, Shi C, Cerezo-Wallis D, Tan Y, et al.
Science
. 2024 Jan;
383(6679):eadf6493.
PMID: 38207030
Neutrophils are increasingly recognized as key players in the tumor immune response and are associated with poor clinical outcomes. Despite recent advances characterizing the diversity of neutrophil states in cancer,...
8.
Yin T, Wang G, Wang L, Mudgal P, Wang E, Pan C, et al.
Nat Immunol
. 2024 Jan;
25(2):268-281.
PMID: 38195702
Melanoma cells, deriving from neuroectodermal melanocytes, may exploit the nervous system's immune privilege for growth. Here we show that nerve growth factor (NGF) has both melanoma cell intrinsic and extrinsic...
9.
Viswanathan R, Cheruba E, Wong P, Yi Y, Ngang S, Chong D, et al.
Sci Adv
. 2023 Sep;
9(37):eadi0197.
PMID: 37713482
5-Methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) are the most abundant DNA modifications that have important roles in gene regulation. Detailed studies of these different epigenetic marks aimed at understanding their combined...
10.
Hamashima K, Wong K, Sam T, Teo J, Taneja R, Le M, et al.
Mol Cell
. 2023 Sep;
PMID: 37657444
N-methyladenosine (mA) RNA modification plays important roles in the governance of gene expression and is temporally regulated in different cell states. In contrast to global mA profiling in bulk sequencing,...