Jessika C Zevenhoven-Dobbe
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Explore the profile of Jessika C Zevenhoven-Dobbe including associated specialties, affiliations and a list of published articles.
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28
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3288
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Recent Articles
1.
Salgado-Benvindo C, Tas A, Zevenhoven-Dobbe J, van der Meer Y, Sidorov I, Leijs A, et al.
Antiviral Res
. 2024 May;
227:105903.
PMID: 38723907
A range of cell culture infection models have been used to study SARS-CoV-2 and perform antiviral drug research. Commonly used African green monkey Vero, human lung-derived Calu-3 and ACE2+TMPRSS2-expressing A549 ...
2.
Ogando N, El Kazzi P, Zevenhoven-Dobbe J, Bontes B, Decombe A, Posthuma C, et al.
Proc Natl Acad Sci U S A
. 2021 Nov;
118(49).
PMID: 34845015
As coronaviruses (CoVs) replicate in the host cell cytoplasm, they rely on their own capping machinery to ensure the efficient translation of their messenger RNAs (mRNAs), protect them from degradation...
3.
Ogando N, Zevenhoven-Dobbe J, van der Meer Y, Bredenbeek P, Posthuma C, Snijder E
J Virol
. 2020 Sep;
94(23).
PMID: 32938769
Coronaviruses (CoVs) stand out for their large RNA genome and complex RNA-synthesizing machinery comprising 16 nonstructural proteins (nsps). The bifunctional nsp14 contains 3'-to-5' exoribonuclease (ExoN) and guanine-N7-methyltransferase (N7-MTase) domains. While...
4.
Carbo E, Sidorov I, Zevenhoven-Dobbe J, Snijder E, Claas E, Laros J, et al.
J Clin Virol
. 2020 Sep;
131:104594.
PMID: 32866812
Introduction: The SARS-CoV-2 pandemic of 2020 is a prime example of the omnipresent threat of emerging viruses that can infect humans. A protocol for the identification of novel coronaviruses by...
5.
Wolff G, Limpens R, Zevenhoven-Dobbe J, Laugks U, Zheng S, de Jong A, et al.
Science
. 2020 Aug;
369(6509):1395-1398.
PMID: 32763915
Coronavirus genome replication is associated with virus-induced cytosolic double-membrane vesicles, which may provide a tailored microenvironment for viral RNA synthesis in the infected cell. However, it is unclear how newly...
6.
Ogando N, Dalebout T, Zevenhoven-Dobbe J, Limpens R, van der Meer Y, Caly L, et al.
J Gen Virol
. 2020 Jun;
101(9):925-940.
PMID: 32568027
The sudden emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at the end of 2019 from the Chinese province of Hubei and its subsequent pandemic spread highlight the importance...
7.
Snijder E, Limpens R, de Wilde A, de Jong A, Zevenhoven-Dobbe J, Maier H, et al.
PLoS Biol
. 2020 Jun;
18(6):e3000715.
PMID: 32511245
Zoonotic coronavirus (CoV) infections, such as those responsible for the current severe acute respiratory syndrome-CoV 2 (SARS-CoV-2) pandemic, cause grave international public health concern. In infected cells, the CoV RNA-synthesizing...
8.
de Wilde A, Zevenhoven-Dobbe J, Beugeling C, Chatterji U, de Jong D, Gallay P, et al.
Virology
. 2017 Dec;
517:148-156.
PMID: 29249267
Cyclophilin A (CypA) is an important host factor in the replication of a variety of RNA viruses. Also the replication of several nidoviruses was reported to depend on CypA, although...
9.
de Wilde A, Falzarano D, Zevenhoven-Dobbe J, Beugeling C, Fett C, Martellaro C, et al.
Virus Res
. 2016 Nov;
228:7-13.
PMID: 27840112
Currently, there is no registered treatment for infections with emerging zoonotic coronaviruses like SARS- and MERS-coronavirus. We here report that in cultured cells low-micromolar concentrations of alisporivir, a non-immunosuppressive cyclosporin...
10.
Lehmann K, Gulyaeva A, Zevenhoven-Dobbe J, Janssen G, Ruben M, Overkleeft H, et al.
Nucleic Acids Res
. 2015 Aug;
43(17):8416-34.
PMID: 26304538
RNA viruses encode an RNA-dependent RNA polymerase (RdRp) that catalyzes the synthesis of their RNA(s). In the case of positive-stranded RNA viruses belonging to the order Nidovirales, the RdRp resides...