Jesse W Williams
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Explore the profile of Jesse W Williams including associated specialties, affiliations and a list of published articles.
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57
Citations
2164
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Recent Articles
1.
Rousseau D, Bonnafous S, Soysouvanh F, Sarrail D, Bourinet M, Strazzulla A, et al.
Hepatology
. 2025 Jan;
PMID: 39808819
Background And Aims: Alcohol-related liver disease (ALD) is one of the leading causes of severe liver disease with limited pharmacological treatments for alcohol-related steatohepatitis (ASH). CD44, a glycoprotein mainly expressed...
2.
Gallerand A, Caillot Z, Terekhova M, Castiglione A, Leporati L, Giacchero M, et al.
bioRxiv
. 2024 Dec;
PMID: 39677815
Macrophages are innate immune cells present in all tissues, in which they participate in immune responses and maintenance of tissue homeostasis. They develop either from embryonic precursors or from circulating...
3.
Williams J, Lutgens E
Nat Cardiovasc Res
. 2024 Nov;
3(12):1380-1382.
PMID: 39613874
No abstract available.
4.
Lyons C, Pallais J, McGonigle S, Mansk R, Collinge C, Yousefzadeh M, et al.
Nat Aging
. 2024 Nov;
5(1):48-64.
PMID: 39528642
Life stress can shorten lifespan and increase risk for aging-related diseases, but the biology underlying this phenomenon remains unclear. Here we assessed the effect of chronic stress on cellular senescence-a...
5.
Gallerand A, Dolfi B, Stunault M, Caillot Z, Castiglione A, Strazzulla A, et al.
Nat Commun
. 2024 Oct;
15(1):9027.
PMID: 39424804
Monocytes directly contribute to atherosclerosis development by their recruitment to plaques in which they differentiate into macrophages. In the present study, we ask how modulating monocyte glucose metabolism could affect...
6.
Kazmirczak F, Vogel N, Prisco S, Patterson M, Annis J, Moon R, et al.
Circ Res
. 2024 Oct;
135(11):1067-1083.
PMID: 39421926
Background: Mitochondrial dysfunction, characterized by impaired lipid metabolism and heightened reactive oxygen species generation, results in lipid peroxidation and ferroptosis. Ferroptosis is an inflammatory mode of cell death that promotes...
7.
Xu Y, Hillman H, Chang M, Ivanov S, Williams J
bioRxiv
. 2024 Oct;
PMID: 39386558
Macrophages are essential immune cells present in all tissues, and are vital for maintaining tissue homeostasis, immune surveillance, and immune responses. Considerable efforts have identified shared and tissue-specific gene programs...
8.
Zhong R, Xu Y, Williams J, Li L
Alzheimers Dement
. 2024 Sep;
20(11):7595-7612.
PMID: 39308178
Introduction: The microglial receptor triggering receptor expressed on myeloid cells 2 (TREM2) is a major risk factor for Alzheimer's disease (AD). Experimentally, Trem2 deficiency affects parenchymal amyloid beta (Aβ) deposition....
9.
Fredrickson G, Florczak K, Barrow F, Mahmud S, Dietsche K, Wang H, et al.
Hepatology
. 2024 Sep;
PMID: 39292863
Background And Aims: For patients with obesity and metabolic syndrome, bariatric procedures such as vertical sleeve gastrectomy (VSG) have a clear benefit in ameliorating metabolic dysfunction-associated steatohepatitis (MASH). While the...
10.
Takaoka M, Zhao X, Lim H, Magnussen C, Ang O, Suffee N, et al.
Nature
. 2024 Sep;
634(8033):457-465.
PMID: 39231480
Hyperlipidaemia is a major risk factor of atherosclerotic cardiovascular disease (ASCVD). Risk of cardiovascular events depends on cumulative lifetime exposure to low-density lipoprotein cholesterol (LDL-C) and, independently, on the time...