Konstantin Zaitsev
Overview
Explore the profile of Konstantin Zaitsev including associated specialties, affiliations and a list of published articles.
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42
Citations
2268
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Recent Articles
1.
Patterson M, Firulyova M, Xu Y, Hillman H, Bishop C, Zhu A, et al.
Nat Cardiovasc Res
. 2024 Apr;
2(11):1015-1031.
PMID: 38646596
Atherosclerosis is driven by the expansion of cholesterol-loaded 'foamy' macrophages in the arterial intima. Factors regulating foamy macrophage differentiation and survival in plaque remain poorly understood. Here we show, using...
2.
Osinski V, Yellamilli A, Firulyova M, Zhang M, Peck A, Auger J, et al.
Arterioscler Thromb Vasc Biol
. 2024 Jan;
44(4):807-821.
PMID: 38269589
Background: Rheumatic heart disease is the major cause of valvular heart disease in developing nations. Endothelial cells (ECs) are considered crucial contributors to rheumatic heart disease, but greater insight into...
3.
Cook M, Shchukina I, Lin C, Bradstreet T, Schwarzkopf E, Jarjour N, et al.
Immunohorizons
. 2023 Nov;
7(11):737-746.
PMID: 37934060
TH17 cells are implicated in the pathogenesis of multiple sclerosis and experimental autoimmune encephalomyelitis (EAE). We previously reported that the transcription factor basic helix-loop-helix family member e40 (BHLHE40) marks cytokine-producing...
4.
Patterson M, Burrack A, Xu Y, Hickok G, Schmiechen Z, Becker S, et al.
Cell Rep
. 2023 Jul;
42(7):112732.
PMID: 37402168
Pancreatic ductal adenocarcinoma (PDA) orchestrates a suppressive tumor microenvironment that fosters immunotherapy resistance. Tumor-associated macrophages (TAMs) are the principal immune cell infiltrating PDA and are heterogeneous. Here, by employing macrophage...
5.
Guilbaud E, Barouillet T, Ilie M, Borowczyk C, Ivanov S, Sarrazy V, et al.
Cell Stem Cell
. 2023 Jun;
30(6):800-817.e9.
PMID: 37267915
Cholesterol efflux pathways could be exploited in tumor biology to unravel cancer vulnerabilities. A mouse model of lung-tumor-bearing KRAS mutation with specific disruption of cholesterol efflux pathways in epithelial progenitor...
6.
Faragher J, Auger J, Osinski V, Meier L, Engelson B, Firulyova M, et al.
Arterioscler Thromb Vasc Biol
. 2023 Apr;
43(6):943-957.
PMID: 37021574
Background: Inflammation is a key driver of cardiovascular pathology, and many systemic autoimmune/rheumatic diseases are accompanied by increased cardiac risk. In the K/B.g7 mouse model of coexisting systemic autoantibody-mediated arthritis...
7.
Burrack A, Spartz E, Rollins M, Miller E, Firulyova M, Cruz E, et al.
Cancer Immunol Immunother
. 2022 Dec;
72(6):1461-1478.
PMID: 36472588
Pancreatic ductal adenocarcinoma (PDA) is a lethal and metastatic malignancy resistant to therapy. Elucidating how pancreatic tumor-specific T cells differentiate and are maintained in vivo could inform novel therapeutic avenues...
8.
Perik-Zavodskii R, Perik-Zavodskaia O, Shevchenko J, Denisova V, Alrhmoun S, Volynets M, et al.
Cells
. 2022 Nov;
11(22).
PMID: 36428967
Nucleated erythroid cells (NECs) are the precursors of erythrocytes. They can be found in various hematopoietic tissues or in the blood. Recently, they have been shown to be active players...
9.
Koenig A, Shchukina I, Amrute J, Andhey P, Zaitsev K, Lai L, et al.
Nat Cardiovasc Res
. 2022 Aug;
1(3):263-280.
PMID: 35959412
Heart failure represents a major cause of morbidity and mortality worldwide. Single-cell transcriptomics have revolutionized our understanding of cell composition and associated gene expression. Through integrated analysis of single-cell and...
10.
Perik-Zavodskii R, Perik-Zavodskaya O, Shevchenko Y, Denisova V, Nazarov K, Obleuhova I, et al.
Genes (Basel)
. 2022 Jul;
13(8).
PMID: 35893070
CD71+ erythroid cells (CECs) were only known as erythrocyte progenitors not so long ago. In present times, however, they have been shown to be active players in immune regulation, especially...