Jesper L Andersen
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Explore the profile of Jesper L Andersen including associated specialties, affiliations and a list of published articles.
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67
Citations
1942
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Recent Articles
1.
Van Den Berg M, Shi Z, Claassen W, Hooijman P, Lewis C, Andersen J, et al.
Sci Transl Med
. 2024 Jul;
16(758):eadg3894.
PMID: 39083588
Patients receiving mechanical ventilation in the intensive care unit (ICU) frequently develop contractile weakness of the diaphragm. Consequently, they may experience difficulty weaning from mechanical ventilation, which increases mortality and...
2.
Soendenbroe C, Karlsen A, Svensson R, Kjaer M, Andersen J, Mackey A
J Cachexia Sarcopenia Muscle
. 2023 Dec;
15(1):306-318.
PMID: 38123165
Background: Age-related loss of strength is disproportionally greater than the loss of mass, suggesting maladaptations in the neuro-myo-tendinous system. Myofibers are often misshaped in aged and diseased muscle, but systematic...
3.
Sonne A, Antonovic A, Melhedegaard E, Akter F, Andersen J, Jungbluth H, et al.
Acta Physiol (Oxf)
. 2023 Aug;
239(2):e14035.
PMID: 37602753
Aim: Conditions related to mutations in the gene encoding the skeletal muscle ryanodine receptor 1 (RYR1) are genetic muscle disorders and include congenital myopathies with permanent weakness, as well as...
4.
Fusion of myofibre branches is a physiological feature of healthy human skeletal muscle regeneration
Hojfeldt G, Sorenson T, Gonzales A, Kjaer M, Andersen J, Mackey A
Skelet Muscle
. 2023 Aug;
13(1):13.
PMID: 37573332
Background: The occurrence of hyperplasia, through myofibre splitting, remains a widely debated phenomenon. Structural alterations and fibre typing of skeletal muscle fibres, as seen during regeneration and in certain muscle...
5.
Physical activity impacts resting skeletal muscle myosin conformation and lowers its ATP consumption
Lewis C, Tabrizian L, Nielsen J, Laitila J, Beck T, Olsen M, et al.
J Gen Physiol
. 2023 May;
155(7).
PMID: 37227464
It has recently been established that myosin, the molecular motor protein, is able to exist in two conformations in relaxed skeletal muscle. These conformations are known as the super-relaxed (SRX)...
6.
Sonne A, Peverelli L, Hernandez-Lain A, Dominguez-Gonzalez C, Andersen J, Milone M, et al.
Am J Physiol Cell Physiol
. 2023 Feb;
324(3):C769-C776.
PMID: 36745529
Congenital myopathies are a vast group of genetic muscle diseases. Among the causes are mutations in the gene resulting in truncated type IIa myosin heavy chains (MyHCs). The precise cellular...
7.
Soendenbroe C, Heisterberg M, Schjerling P, Kjaer M, Andersen J, Mackey A
Am J Physiol Cell Physiol
. 2022 Jun;
323(1):C159-C169.
PMID: 35649253
Muscle fiber denervation is a major contributor to the decline in muscle mass and function during aging. Heavy resistance exercise is an effective tool for increasing muscle mass and strength,...
8.
Soendenbroe C, Dahl C, Meulengracht C, Tamas M, Svensson R, Schjerling P, et al.
J Physiol
. 2022 Mar;
600(8):1969-1989.
PMID: 35229299
Muscle fibre denervation and declining numbers of muscle stem (satellite) cells are defining characteristics of ageing skeletal muscle. The aim of this study was to investigate the potential for lifelong...
9.
Soendenbroe C, Andersen J, Mackey A
Am J Physiol Cell Physiol
. 2021 Jun;
321(2):C317-C329.
PMID: 34161153
Muscle fiber denervation is a major contributor to the decline in physical function observed with aging. Denervation can occur through breakdown of the neuromuscular junctions (NMJ) itself, affecting only that...
10.
Fristrup B, Krustrup P, Andersen J, Hornstrup T, Lowenstein F, Larsen M, et al.
PLoS One
. 2020 Nov;
15(11):e0241359.
PMID: 33206670
Prolonged physical inactivity in young adults may lead to deficiencies in musculoskeletal fitness, and thus a need exists to develop physical activity and exercise programmes that are effective of increasing...