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Abigail L Mackey

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Articles 69
Citations 1244
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Recent Articles
1.
Soendenbroe C, Boraxbekk C, Mackey A
J Physiol . 2025 Jan; PMID: 39761204
Short-term disuse leads to rapid declines in muscle mass and strength. These declines are driven by changes at all levels of the neuromuscular system; the brain, spinal cord and skeletal...
2.
Hoegsbjerg C, Mobjerg A, Yeung C, Schjerling P, Krogsgaard M, Koch M, et al.
J Cell Sci . 2024 Dec; 138(2. PMID: 39704232
The myotendinous junction (MTJ) is a weak link in the musculoskeletal system. Here, we isolated the tips of single myofibres from healthy (non-injured) human hamstring muscles for confocal microscopy (n=6)...
3.
Soendenbroe C, Schjerling P, Bechshoft C, Svensson R, Schaeffer L, Kjaer M, et al.
Aging Cell . 2024 Nov; 24(3):e14413. PMID: 39555723
Exercise preserves neuromuscular function in aging through unknown mechanisms. Skeletal muscle fibroblasts (FIB) and stem cells (MuSC) are abundant in skeletal muscle and reside close to neuromuscular junctions, but their...
4.
Wulff M, Mackey A, Kjaer M, Bayer M
Transl Sports Med . 2024 Sep; 2024:2336376. PMID: 39263259
A major challenge in sports medicine is to facilitate the fastest possible recovery from injury without increasing the risk of subsequent reruptures, and thus effective rehabilitation programs should balance between...
5.
Mackey A
Cold Spring Harb Perspect Biol . 2024 Aug; PMID: 39134380
A critical link in the chain of force transmission from muscle fiber cross-bridge to bone is the interface between muscle and tendon-the myotendinous junction (MTJ). To meet the challenge of...
6.
Tangbjerg M, Damgaard A, Karlsen A, Svensson R, Schjerling P, Gelabert-Rebato M, et al.
Exp Physiol . 2024 Jul; 109(9):1529-1544. PMID: 38980930
Prematurity has physical consequences, such as lower birth weight, decreased muscle mass and increased risk of adult-onset metabolic disease. Insulin-like growth factor 1 (IGF-1) has therapeutic potential to improve the...
7.
Merkel M, Svensson R, Jakobsen J, Mackey A, Schjerling P, Herzog R, et al.
Am J Sports Med . 2024 May; 52(7):1834-1844. PMID: 38708721
Background: Plantar fasciitis is a painful tendinous condition (tendinopathy) with a high prevalence in athletes. While a healthy tendon has limited blood flow, ultrasound has indicated elevated blood flow in...
8.
Ruple B, Mattingly M, Godwin J, McIntosh M, Kontos N, Agyin-Birikorang A, et al.
FASEB J . 2024 Apr; 38(8):e23621. PMID: 38651653
Denervated myofibers and senescent cells are hallmarks of skeletal muscle aging. However, sparse research has examined how resistance training affects these outcomes. We investigated the effects of unilateral leg extensor...
9.
Soendenbroe C, Karlsen A, Svensson R, Kjaer M, Andersen J, Mackey A
J Cachexia Sarcopenia Muscle . 2023 Dec; 15(1):306-318. PMID: 38123165
Background: Age-related loss of strength is disproportionally greater than the loss of mass, suggesting maladaptations in the neuro-myo-tendinous system. Myofibers are often misshaped in aged and diseased muscle, but systematic...
10.
Edouard P, Reurink G, Mackey A, Lieber R, Pizzari T, Jarvinen T, et al.
Nat Rev Dis Primers . 2023 Oct; 9(1):56. PMID: 37857686
Traumatic muscle injury represents a collection of skeletal muscle pathologies caused by trauma to the muscle tissue and is defined as damage to the muscle tissue that can result in...