Jerry H Wang
Overview
Explore the profile of Jerry H Wang including associated specialties, affiliations and a list of published articles.
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13
Citations
450
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Recent Articles
1.
Wan J, Fu A, Ip F, Ng H, Hugon J, Page G, et al.
J Neurosci
. 2010 May;
30(20):6873-81.
PMID: 20484629
One of the pathological hallmarks of Alzheimer's disease (AD) is deposition of extracellular amyloid-beta (Abeta) peptide, which is generated from the cleavage of amyloid precursor protein (APP). Accumulation of Abeta...
2.
Fu A, Ip F, Fu W, Cheung J, Wang J, Yung W, et al.
Proc Natl Acad Sci U S A
. 2005 Oct;
102(42):15224-9.
PMID: 16203963
Cyclin-dependent kinase (Cdk)5 is a key regulator of neural development. We have previously demonstrated that Cdk5/p35 are localized to the postsynaptic muscle and are implicated in the regulation of neuregulin/ErbB...
3.
Yu Y, Chen B, Chen Z, Fan C, Han Y, Zhang J, et al.
Biochim Biophys Acta
. 2005 Apr;
1729(1):1-9.
PMID: 15804487
We have identified a novel isoform of Wee1 kinase (Wee1i), which uses Met215 of Wee1 as its initiation codon. RT-PCR, Western blot, and in situ hybridization verified wee1i expression in...
4.
Fu A, Fu W, Ng A, Chien W, Ng Y, Wang J, et al.
Proc Natl Acad Sci U S A
. 2004 Apr;
101(17):6728-33.
PMID: 15096606
The activity of cyclin-dependent kinase 5 (Cdk5) depends on the association with one of its activators, p35 and p39, which are prominently expressed in the nervous system. Studies on the...
5.
Song Y, Kesuma D, Wang J, Deng Y, Duan J, Wang J, et al.
Biochem Biophys Res Commun
. 2004 Mar;
317(1):128-32.
PMID: 15047157
As key regulators of the cell proliferation cycle, cyclin-dependent kinases (CDKs) are attractive targets for the development of anti-tumor drugs. In the present study, harmine was identified from a collection...
6.
Qi R, Ching Y, Kung H, Wang J
FEBS Lett
. 2004 Mar;
561(1-3):177-80.
PMID: 15013773
Cyclin-dependent kinase 5 (Cdk5) in association with its neuronal activators p35 and p39 shows a complex involvement in the control of neurocytoskeletal dynamics. Here we show that alpha-chimaerin, a GTPase-activating...
7.
Wang J, Liu S, Fu Y, Wang J, Lu Y
Nat Neurosci
. 2003 Sep;
6(10):1039-47.
PMID: 14502288
CA1 pyramidal neurons degenerate after transient forebrain ischemia, whereas neurons in other regions of the hippocampus remain intact. Here we show that in rat hippocampal CA1 neurons, forebrain ischemia induces...
8.
Deng Y, Pang A, Wang J
J Biol Chem
. 2003 Jan;
278(14):11760-7.
PMID: 12554736
Mammalian STE20-like kinase 2 (MST2), a member of the STE20-like kinase family, has been shown in previous studies to undergo proteolytic activation by caspase-3 during cell apoptosis. A few studies...
9.
Cheng K, Li Z, Fu W, Wang J, Fu A, Ip N
J Biol Chem
. 2002 Jun;
277(35):31988-93.
PMID: 12084709
Cyclin-dependent kinase 5 (Cdk5) is a serine/threonine kinase that plays important roles during central nervous system development. Cdk5 kinase activity depends on its regulatory partners, p35 or p39, which are...
10.
Fu W, Wang J, Ip N
J Neurochem
. 2002 Jun;
81(3):646-54.
PMID: 12065673
We have recently developed a rapid protocol involving NT2 cell aggregation and treatment with retinoic acid (RA) to produce terminally differentiated CNS neurons. As a first step to explore the...