Jeronimo Jurado-Arjona
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Explore the profile of Jeronimo Jurado-Arjona including associated specialties, affiliations and a list of published articles.
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22
Citations
563
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Recent Articles
1.
Fan W, Jurado-Arjona J, Alanis-Lobato G, Peron S, Berger C, Andrade-Navarro M, et al.
EMBO J
. 2023 Apr;
42(11):e110384.
PMID: 37083045
Most adult hippocampal neural stem cells (NSCs) remain quiescent, with only a minor portion undergoing active proliferation and neurogenesis. The molecular mechanisms that trigger the transition from quiescence to activation...
2.
Extensive transcriptional and chromatin changes underlie astrocyte maturation in vivo and in culture
Lattke M, Goldstone R, Ellis J, Boeing S, Jurado-Arjona J, Marichal N, et al.
Nat Commun
. 2021 Jul;
12(1):4335.
PMID: 34267208
Astrocytes have essential functions in brain homeostasis that are established late in differentiation, but the mechanisms underlying the functional maturation of astrocytes are not well understood. Here we identify extensive...
3.
Samaranch L, Perez-Canamas A, Soto-Huelin B, Sudhakar V, Jurado-Arjona J, Hadaczek P, et al.
Sci Transl Med
. 2019 Aug;
11(506).
PMID: 31434754
Niemann-Pick disease type A (NPD-A) is a lysosomal storage disorder characterized by neurodegeneration and early death. It is caused by loss-of-function mutations in the gene encoding for acid sphingomyelinase (ASM),...
4.
Moreno-Jimenez E, Jurado-Arjona J, Avila J, Llorens-Martin M
Front Cell Dev Biol
. 2019 May;
7:62.
PMID: 31080799
In rodents, the hippocampal dentate gyrus gives rise to newly generated dentate granule cells (DGCs) throughout life. This process, named adult hippocampal neurogenesis (AHN), converges in the functional integration of...
5.
Jurado-Arjona J, Rodriguez-Matellan A, Avila J, Hernandez F
Brain Res
. 2019 Feb;
1712:47-54.
PMID: 30711399
We have studied the consequences of in vivo GSK3β overexpression in the cerebellum using transgenic mice with conditional expression where the transactivator tTA protein expression is driven by GFAP promoter....
6.
Beamer E, Jurado-Arjona J, Jimenez-Mateos E, Morgan J, Reschke C, Kenny A, et al.
Front Mol Neurosci
. 2019 Jan;
11:442.
PMID: 30618601
Prolonged seizures (status epilepticus, SE) may drive hippocampal dysfunction and epileptogenesis, at least partly, through an elevation in neurogenesis, dysregulation of migration and aberrant dendritic arborization of newly-formed neurons. MicroRNA-22...
7.
Pose-Utrilla J, Garcia-Guerra L, Del Puerto A, Martin A, Jurado-Arjona J, De Leon-Reyes N, et al.
Nat Commun
. 2018 Feb;
9(1):473.
PMID: 29382840
The original version of this Article contained an error in the spelling of the author Álvaro Sebastián-Serrano, which was incorrectly given as Álvaro Sebastián Serrano. This has now been corrected...
8.
Pose-Utrilla J, Garcia-Guerra L, Del Puerto A, Martin A, Jurado-Arjona J, De Leon-Reyes N, et al.
Nat Commun
. 2017 Dec;
8(1):2275.
PMID: 29273751
Excitotoxicity, a critical process in neurodegeneration, induces oxidative stress and neuronal death through mechanisms largely unknown. Since oxidative stress activates protein kinase D1 (PKD1) in tumor cells, we investigated the...
9.
Bolos M, Llorens-Martin M, Ramon Perea J, Jurado-Arjona J, Rabano A, Hernandez F, et al.
Mol Neurodegener
. 2017 Aug;
12(1):59.
PMID: 28810892
Background: Extracellular Tau is toxic for neighboring cells, and it contributes to the progression of AD. The CX3CL1/CX3CR1 axis is an important neuron/microglia communication mechanism. Methods: We studied Tau clearance...
10.
Benvegnu S, Mateo M, Palomer E, Jurado-Arjona J, Dotti C
Mol Cell
. 2017 May;
66(3):358-372.e7.
PMID: 28475871
A decline in proteasome function is causally connected to neuronal aging and aging-associated neuropathologies. By using hippocampal neurons in culture and in vivo, we show that aging triggers a reduction...