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Jesus Avila

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Articles 371
Citations 10731
Followers 0
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Recent Articles
1.
Anton-Fernandez A, Ruiz de Alegria A, Mariscal-Casero A, Roldan-Lazaro M, Peinado-Cauchola R, Avila J, et al.
Prog Neurobiol . 2025 Feb; 247:102743. PMID: 40021076
Partial reprogramming induced by the controlled and cyclical overexpression of Yamanaka factors in the nervous system has so far succeeded in reversing some aging-associated phenotypes, such as improving memory function....
2.
Merino-Serrais P, Soria J, Arrabal C, Ortigado-Lopez A, Esparza M, Munoz A, et al.
Exp Neurol . 2024 Nov; 383:115049. PMID: 39522802
Tau has a wide variety of essential functions in the brain, but this protein also plays a determining role in the development of Alzheimer's disease (AD) and other neurodegenerative diseases...
3.
Moreira P, Avila J, Galimberti D, Pappolla M, Plascencia-Villa G, Sorensen A, et al.
J Alzheimers Dis . 2024 Oct; 101(s1):S1-S2. PMID: 39422966
No abstract available.
4.
Anton-Fernandez A, Cauchola R, Hernandez F, Avila J
Aging Cell . 2024 Oct; 24(1):e14365. PMID: 39380362
The Izpisua-Belmonte group identified a cocktail of metabolites that promote partial reprogramming in cultured muscle cells. We tested the effect of brain injection of these metabolites in the dentate gyrus...
5.
Sala-Jarque J, Gil V, Andres-Benito P, Martinez-Soria I, Picon-Pages P, Hernandez F, et al.
Sci Rep . 2024 Sep; 14(1):21622. PMID: 39284839
The cellular prion protein (PrP) plays many roles in the developing and adult brain. In addition, PrP binds to several amyloids in oligomeric and prefibrillar forms and may act as...
6.
Avila J
J Alzheimers Dis . 2024 Jul; 100(s1):S265-S270. PMID: 39058443
Aging is the main risk for neurodegenerative disorders like Alzheimer's disease. In this short review, I will comment on how delaying brain aging through the addition of Yamanaka Factors or...
7.
Avila J, Marco J, Plascencia-Villa G, Bajic V, Perry G
Front Neurosci . 2024 Jul; 18:1430432. PMID: 38979125
No abstract available.
8.
Anton-Fernandez A, Roldan-Lazaro M, Valles-Saiz L, Avila J, Hernandez F
Commun Biol . 2024 May; 7(1):631. PMID: 38789561
In recent years, there has been success in partially reprogramming peripheral organ cells using cyclic Yamanaka transcription factor (YF) expression, resulting in the reversal of age-related pathologies. In the case...
9.
Anton-Fernandez A, Cuadros R, Peinado-Cahuchola R, Hernandez F, Avila J
Sci Rep . 2024 Mar; 14(1):6915. PMID: 38519576
Neuronal aging may be, in part, related to a change in DNA methylation. Thus, methyl donors, like folate and methionine, may play a role in cognitive changes associated to neuronal...
10.
Ruiz-Gabarre D, Valles-Saiz L, Carnero-Espejo A, Ferrer I, Hernandez F, Garcia-Escudero R, et al.
EBioMedicine . 2024 Jan; 100:104953. PMID: 38181704
Background: Tau is a microtubule-binding protein encoded by the MAPT gene. Tau is essential for several physiological functions and associated with pathological processes, including Alzheimer's disease (AD). Six tau isoforms...