Jeroen Pouwels
Overview
Explore the profile of Jeroen Pouwels including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
31
Citations
660
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Turpin R, Peltonen K, Rannikko J, Liu R, Kumari A, Nicorici D, et al.
Oncoimmunology
. 2025 Feb;
14(1):2466305.
PMID: 39960413
Tumor-resident immune cells play a crucial role in eliciting anti-tumor immunity and immunomodulatory drug responses, yet these functions have been difficult to study without tractable models of the tumor immune...
2.
Turpin R, Liu R, Munne P, Peura A, Rannikko J, Philips G, et al.
J Immunother Cancer
. 2024 Apr;
12(4).
PMID: 38604809
Background: Combining cytotoxic chemotherapy or novel anticancer drugs with T-cell modulators holds great promise in treating advanced cancers. However, the response varies depending on the tumor immune microenvironment (TIME). Therefore,...
3.
Belitskin D, Munne P, Pant S, Anttila J, Suleymanova I, Belitskina K, et al.
Mol Oncol
. 2023 Oct;
18(3):547-561.
PMID: 37872868
Hepsin, a type II transmembrane serine protease, is commonly overexpressed in prostate and breast cancer. The hepsin protein is stabilized by the Ras-MAPK pathway, and, downstream, this protease regulates the...
4.
Khan M, Salomaa S, Jacquemet G, Butt U, Miihkinen M, Deguchi T, et al.
J Cell Sci
. 2023 Oct;
136(19).
PMID: 37823537
No abstract available.
5.
Butt U, Khan M, Pouwels J, Westermarck J
J Cell Sci
. 2022 Sep;
135(20).
PMID: 36148554
SHARPIN is involved in several cellular processes and promotes cancer progression. However, how the choice between different functions of SHARPIN is post-translationally regulated is unclear. Here, we characterized SHARPIN phosphorylation...
6.
Cvrljevic A, Butt U, Huhtinen K, Gronroos T, Bockelman C, Lassus H, et al.
Mol Cancer Ther
. 2022 Apr;
21(7):1236-1245.
PMID: 35364610
Identification of ovarian cancer patient subpopulations with increased sensitivity to targeted therapies could offer significant clinical benefit. We report that 22% of the high-grade ovarian cancer tumors at diagnosis express...
7.
Munne P, Martikainen L, Raty I, Bertula K, Nonappa , Ruuska J, et al.
Nat Commun
. 2021 Nov;
12(1):6967.
PMID: 34845227
Breast cancer is now globally the most frequent cancer and leading cause of women's death. Two thirds of breast cancers express the luminal estrogen receptor-positive (ERα + ) phenotype that...
8.
Belitskin D, Pant S, Munne P, Suleymanova I, Belitskina K, Hongisto H, et al.
EMBO Rep
. 2021 Sep;
22(11):e52532.
PMID: 34515392
Transforming growth factor-beta (TGFβ) is a multifunctional cytokine with a well-established role in mammary gland development and both oncogenic and tumor-suppressive functions. The extracellular matrix (ECM) indirectly regulates TGFβ activity...
9.
Utz B, Turpin R, Lampe J, Pouwels J, Klefstrom J
Sci Rep
. 2020 Oct;
10(1):18733.
PMID: 33127915
Breast cancer is the most common form of cancer in women. Despite significant therapeutic advances in recent years, breast cancer also still causes the greatest number of cancer-related deaths in...
10.
Peuhu E, Salomaa S, De Franceschi N, Potter C, Sundberg J, Pouwels J
PLoS One
. 2017 Oct;
12(10):e0186628.
PMID: 29040328
SHARPIN (Shank-Associated RH Domain-Interacting Protein) is a component of the linear ubiquitin chain assembly complex (LUBAC), which enhances TNF-induced NF-κB activity. SHARPIN-deficient (Sharpincpdm/cpdm) mice display multi-organ inflammation and chronic proliferative...