Jernej Wagger
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Explore the profile of Jernej Wagger including associated specialties, affiliations and a list of published articles.
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4
Citations
8
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Recent Articles
1.
Vah L, Medved T, Groselj U, Klemencic M, Podlipnik C, Stefane B, et al.
Molecules
. 2022 Jul;
27(15).
PMID: 35897941
In silico evaluation of various regioisomeric 5- and 3-hydroxy-substituted alkyl 1-aryl-1-pyrazole-4-carboxylates and their acyclic precursors yielded promising results with respect to their binding in the active site of dihydroorotate dehydrogenase...
2.
Strasek N, Lavrencic L, Ostrek A, Slapsak D, Groselj U, Klemencic M, et al.
Bioorg Chem
. 2019 May;
89:102982.
PMID: 31132601
The reactions between 5-substituted pyrazolidine-3-ones, aldehydes, and methyl methacrylate provided tetrahydropyrazolo[1,2-a]pyrazole-1-carboxylates as mixtures of syn- and anti-diastereomers. Testing for inhibition of dihydroorotate dehydrogenase of Plasmodium falciparum (PfDHODH) revealed high activity...
3.
Hanessian S, Wagger J, Merner B, Giacometti R, Ostergaard M, Swayze E, et al.
J Org Chem
. 2013 Aug;
78(18):9064-75.
PMID: 23937256
A constrained tricyclic analogue of α-L-LNA (2), which contains dual modes of conformational restriction about the ribose sugar moiety, has been synthesized and characterized by X-ray crystallography. Thermal denaturation experiments...
4.
Cebasek P, Wagger J, Bevk D, Jakse R, Svete J, Stanovnik B
J Comb Chem
. 2004 May;
6(3):356-62.
PMID: 15132595
N-Protected (Z)-3-(arylamino)-2,3-dehydroalanine esters 5 and 10 were prepared in one step from methyl (Z)-2-acylamino-3-(dimethylamino)prop-2-enoates 3 and 9 and anilines 4 employing a parallel solution-phase synthetic approach. In most cases, analytically...