Jeremy M Rock
Overview
Explore the profile of Jeremy M Rock including associated specialties, affiliations and a list of published articles.
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30
Citations
2279
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Recent Articles
1.
Bosch B, DeJesus M, Schnappinger D, Rock J
Ann N Y Acad Sci
. 2024 Apr;
1535(1):10-19.
PMID: 38595325
Mycobacterium tuberculosis remains the most common infectious killer worldwide despite decades of antitubercular drug development. Effectively controlling the tuberculosis (TB) pandemic will require innovation in drug discovery. In this review,...
2.
Eckartt K, Delbeau M, Munsamy-Govender V, DeJesus M, Azadian Z, Reddy A, et al.
Nature
. 2024 Mar;
628(8006):186-194.
PMID: 38509362
Drug-resistant bacteria are emerging as a global threat, despite frequently being less fit than their drug-susceptible ancestors. Here we sought to define the mechanisms that drive or buffer the fitness...
3.
Ju X, Li S, Froom R, Wang L, Lilic M, Delbeau M, et al.
Nature
. 2024 Feb;
627(8003):424-430.
PMID: 38418874
Mycobacterium tuberculosis (Mtb) is a bacterial pathogen that causes tuberculosis (TB), an infectious disease that is responsible for major health and economic costs worldwide. Mtb encounters diverse environments during its...
4.
Poulton N, DeJesus M, Munsamy-Govender V, Kanai M, Roberts C, Azadian Z, et al.
Cell Chem Biol
. 2024 Jan;
31(4):669-682.e7.
PMID: 38266648
Pathogenic mycobacteria are a significant cause of morbidity and mortality worldwide. The conserved whiB7 stress response reduces the effectiveness of antibiotic therapy by activating several intrinsic antibiotic resistance mechanisms. Despite...
5.
Poulton N, DeJesus M, Munsamy-Govender V, Roberts C, Azadian Z, Bosch B, et al.
bioRxiv
. 2023 Jun;
PMID: 37333137
Pathogenic mycobacteria are a significant cause of morbidity and mortality worldwide. These bacteria are highly intrinsically drug resistant, making infections challenging to treat. The conserved stress response is a key...
6.
Ju X, Li S, Froom R, Wang L, Lilic M, Campbell E, et al.
bioRxiv
. 2023 Mar;
PMID: 36945399
(Mtb) is a bacterial pathogen that causes tuberculosis, an infectious disease that inflicts major health and economic costs around the world . Mtb encounters a diversity of environments during its...
7.
Poulton N, Rock J
Front Cell Infect Microbiol
. 2022 Nov;
12:997283.
PMID: 36325467
Tuberculosis (TB) is among the most difficult infections to treat, requiring several months of multidrug therapy to produce a durable cure. The reasons necessitating long treatment times are complex and...
8.
Poulton N, Azadian Z, DeJesus M, Rock J
Antimicrob Agents Chemother
. 2022 Aug;
66(9):e0090422.
PMID: 35920665
Tuberculosis (TB) is the leading cause of death from any bacterial infection, causing 1.5 million deaths worldwide each year. Due to the emergence of drug-resistant strains of Mycobacterium tuberculosis (Mtb)...
9.
Theriault M, Pisu D, Wilburn K, Le-Bury G, MacNamara C, Petrassi H, et al.
Commun Biol
. 2022 Jul;
5(1):685.
PMID: 35810253
Mycobacterium tuberculosis (Mtb), the cause of the human pulmonary disease tuberculosis (TB), contributes to approximately 1.5 million deaths every year. Prior work has established that lipids are actively catabolized by...
10.
Li S, Poulton N, Chang J, Azadian Z, DeJesus M, Ruecker N, et al.
Nat Microbiol
. 2022 May;
7(6):766-779.
PMID: 35637331
Mycobacterium tuberculosis (Mtb) infection is notoriously difficult to treat. Treatment efficacy is limited by Mtb's intrinsic drug resistance, as well as its ability to evolve acquired resistance to all antituberculars...