Jeremy J Velazquez
Overview
Explore the profile of Jeremy J Velazquez including associated specialties, affiliations and a list of published articles.
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12
Citations
462
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Recent Articles
1.
Hislop J, Song Q, Keshavarz F K, Alavi A, Schoenberger R, LeGraw R, et al.
Nature
. 2023 Dec;
626(7998):367-376.
PMID: 38092041
Implantation of the human embryo begins a critical developmental stage that comprises profound events including axis formation, gastrulation and the emergence of haematopoietic system. Our mechanistic knowledge of this window...
2.
Lo E, Velazquez J, Peng D, Kwon C, Ebrahimkhani M, Cahan P
Stem Cell Reports
. 2023 Jul;
18(8):1721-1742.
PMID: 37478860
Optimization of cell engineering protocols requires standard, comprehensive quality metrics. We previously developed CellNet, a computational tool to quantitatively assess the transcriptional fidelity of engineered cells compared with their natural...
3.
Li D, Velazquez J, Ding J, Hislop J, Ebrahimkhani M, Bar-Joseph Z
Genome Biol
. 2022 Mar;
23(1):73.
PMID: 35255944
A major advantage of single cell RNA-sequencing (scRNA-Seq) data is the ability to reconstruct continuous ordering and trajectories for cells. Here we present TraSig, a computational method for improving the...
4.
Velazquez J, Ebrahimkhani M
Transpl Int
. 2021 May;
34(6):999-1001.
PMID: 33977592
No abstract available.
5.
Carter S, Hislop J, Hsu J, Velazquez J, Ebrahimkhani M
Methods Mol Biol
. 2020 Dec;
2258:17-28.
PMID: 33340351
Cell-fate determination is a function of cell-intrinsic and -extrinsic signaling cues. Understanding the design principles governing fate control in multicellular systems remains difficult to understand and analyze. To address the...
6.
Velazquez J, LeGraw R, Moghadam F, Tan Y, Kilbourne J, Maggiore J, et al.
Cell Syst
. 2020 Dec;
12(1):41-55.e11.
PMID: 33290741
Pluripotent stem cell (PSC)-derived organoids have emerged as novel multicellular models of human tissue development but display immature phenotypes, aberrant tissue fates, and a limited subset of cells. Here, we...
7.
Moghadam F, LeGraw R, Velazquez J, Yeo N, Xu C, Park J, et al.
Nat Cell Biol
. 2020 Sep;
22(9):1143-1154.
PMID: 32884147
Transient modulation of the genes involved in immunity, without exerting a permanent change in the DNA code, can be an effective strategy to modulate the course of many inflammatory conditions....
8.
Edington C, Chen W, Geishecker E, Kassis T, Soenksen L, Bhushan B, et al.
Sci Rep
. 2018 Mar;
8(1):4530.
PMID: 29540740
Microphysiological systems (MPSs) are in vitro models that capture facets of in vivo organ function through use of specialized culture microenvironments, including 3D matrices and microperfusion. Here, we report an...
9.
Velazquez J, Su E, Cahan P, Ebrahimkhani M
Trends Biotechnol
. 2017 Dec;
36(4):415-429.
PMID: 29229492
Mammalian tissue development is an intricate, spatiotemporal process of self-organization that emerges from gene regulatory networks of differentiating stem cells. A major goal in stem cell biology is to gain...
10.
Chen W, Edington C, Suter E, Yu J, Velazquez J, Velazquez J, et al.
Biotechnol Bioeng
. 2017 Jul;
114(11):2648-2659.
PMID: 28667746
A capability for analyzing complex cellular communication among tissues is important in drug discovery and development, and in vitro technologies for doing so are required for human applications. A prominent...