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Jeremy B Ducharme

Explore the profile of Jeremy B Ducharme including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 31
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Recent Articles
1.
Bailly A, Hester G, Alesi M, Buresh R, Feito Y, Mermier C, et al.
J Bone Miner Metab . 2025 Mar; PMID: 40053115
Introduction: This study aimed to investigate the effects of quercetin (a plant-based flavonoid) supplementation over 90 days on prominent bone turnover markers (BTMs), inflammatory markers, bone mineral density (BMD), body...
2.
Ducharme J, Carelock M, Schonk M, Al-Zaeed N, Zhang W, Judge S, et al.
Am J Physiol Cell Physiol . 2025 Feb; PMID: 39993009
Cancer cachexia is the involuntary loss of body and skeletal muscle mass, which negatively impacts physical function, quality of life, treatment tolerance, and survival. Skeletal muscles of cachectic people and...
3.
Ducharme J, Specht J, Bailly A, Fennel Z, Nava R, Mermier C, et al.
Med Sci Sports Exerc . 2024 Dec; 57(4):767-780. PMID: 39625335
Introduction: A bout of vigorous endurance exercise transiently activates Toll-like receptor 4 (TLR4) and reduces TLR4 protein expressed on peripheral blood mononuclear cells (PBMCs). Endurance training, on the other hand,...
4.
Schonk M, Ducharme J, Neyroud D, Nosacka R, Tucker H, Judge S, et al.
Am J Physiol Cell Physiol . 2024 Nov; 328(1):C1-C8. PMID: 39545377
Cancer cachexia affects up to 80% of patients with cancer and results in reduced quality of life and survival. We previously demonstrated that the transcriptional repressor Forkhead box P1 (FoxP1)...
5.
Schonk M, Ducharme J, Neyroud D, Nosacka R, Tucker H, Judge S, et al.
bioRxiv . 2024 Sep; PMID: 39345535
Cancer cachexia affects up to 80% of cancer patients and results in reduced quality of life and survival. We previously demonstrated that the transcriptional repressor Forkhead box P1 (FoxP1) is...
6.
Ducharme J, McKenna Z, Specht J, Fennel Z, Berkemeier Q, Deyhle M
J Appl Physiol (1985) . 2023 Nov; 136(1):33-42. PMID: 37994415
Exercise in hypoxia increases immune responses compared with normoxic exercise, and while Toll-like receptor 4 (TLR4) is implicated in these responses, its regulation remains undefined. The purpose of this study...
7.
Fennel Z, Ducharme J, Berkemeier Q, Specht J, McKenna Z, Simpson S, et al.
Am J Physiol Regul Integr Comp Physiol . 2023 Oct; 325(6):R735-R749. PMID: 37842742
Muscle mass is balanced between hypertrophy and atrophy by cellular processes, including activation of the protein kinase B-mechanistic target of rapamycin (Akt-mTOR) signaling cascade. Stressors apart from exercise and nutrition,...
8.
Ducharme J, Fennel Z, McKenna Z, Nava R, Deyhle M
Am J Physiol Cell Physiol . 2023 Jun; 325(1):C300-C313. PMID: 37335026
Toll-like receptor 4 (TLR4) activation by lipopolysaccharides (LPS) increases proinflammatory cytokine production and upregulation of muscle atrophy signaling pathways. Muscle contractions can suppress LPS/TLR4 axis activation by reducing the protein...
9.
McKenna Z, Bellovary B, Ducharme J, Deyhle M, Wells A, Fennel Z, et al.
Eur J Sport Sci . 2023 Apr; 23(10):2002-2010. PMID: 37051668
Hypoxia induced intestinal barrier injury, microbial translocation, and local/systemic inflammation may contribute to high-altitude associated gastrointestinal complications or symptoms of acute mountain sickness (AMS). Therefore, we tested the hypothesis that...
10.
Ducharme J, Hall H, Fennel Z, Gerard-Osbourne A, Houck J, Clark C, et al.
J Electr Bioimpedance . 2023 Jan; 13(1):96-105. PMID: 36694882
Bioelectrical impedance analysis (BIA) reference values are based on supine assessments. Little is known regarding the effects of time course shifts in body water compartments after assuming a supine position....