Michael R Deyhle
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Explore the profile of Michael R Deyhle including associated specialties, affiliations and a list of published articles.
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29
Citations
236
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Recent Articles
1.
Neyroud D, DLugos A, Trevino E, Callaway C, Lamm J, Laitano O, et al.
J Cachexia Sarcopenia Muscle
. 2025 Jan;
16(1):e13668.
PMID: 39810606
Background: Cancer cachexia represents a debilitating muscle wasting condition that is highly prevalent in gastrointestinal cancers, including pancreatic ductal adenocarcinoma (PDAC). Cachexia is estimated to contribute to ~30% of cancer-related...
2.
Ducharme J, Specht J, Bailly A, Fennel Z, Nava R, Mermier C, et al.
Med Sci Sports Exerc
. 2024 Dec;
57(4):767-780.
PMID: 39625335
Introduction: A bout of vigorous endurance exercise transiently activates Toll-like receptor 4 (TLR4) and reduces TLR4 protein expressed on peripheral blood mononuclear cells (PBMCs). Endurance training, on the other hand,...
3.
Leslie E, Gonzalez Bosc L, Specht J, McKenna Z, Gridley R, Luna V, et al.
Med Sci Sports Exerc
. 2024 May;
56(10):1867-1881.
PMID: 38768014
Purpose: Chronic, high-altitude hypoxic exposure increases the risk of high-altitude pulmonary hypertension (PH). Emerging evidence shows maternal exercise may improve offspring resistance to disease throughout life. The purpose of this...
4.
Berkemeier Q, Deyhle M, McCormick J, Escobar K, Mermier C
High Alt Med Biol
. 2024 May;
25(4):326-336.
PMID: 38700877
Berkemeier, Quint N., Michael R. Deyhle, James J. McCormick, Kurt A. Escobar, and Christine M. Mermier. The potential interplay between HIF-1α, angiogenic, and autophagic signaling during intermittent hypoxic exposure and...
5.
Masoud A, McKenna Z, Li Z, Deyhle M, Mermier C, Schlader Z, et al.
Am J Physiol Renal Physiol
. 2024 Feb;
PMID: 38299216
Prolonged physical work in the heat can reduce renal function and increase the risk of acute kidney injury (AKI). This is concerning given that the latest climate change projections forecast...
6.
Deyhle M, Tiede D, Xin L, Hyldahl R, Hubal M
Med Sci Sports Exerc
. 2024 Jan;
56(6):1108-1117.
PMID: 38294822
Purpose: Unaccustomed eccentric (ECC) exercise evokes exercise-induced muscle damage (EIMD). Soreness, strength loss, and serum creatine kinase (CK) are often used to quantify EIMD severity. However, changes in these markers...
7.
Ducharme J, McKenna Z, Specht J, Fennel Z, Berkemeier Q, Deyhle M
J Appl Physiol (1985)
. 2023 Nov;
136(1):33-42.
PMID: 37994415
Exercise in hypoxia increases immune responses compared with normoxic exercise, and while Toll-like receptor 4 (TLR4) is implicated in these responses, its regulation remains undefined. The purpose of this study...
8.
Fennel Z, Ducharme J, Berkemeier Q, Specht J, McKenna Z, Simpson S, et al.
Am J Physiol Regul Integr Comp Physiol
. 2023 Oct;
325(6):R735-R749.
PMID: 37842742
Muscle mass is balanced between hypertrophy and atrophy by cellular processes, including activation of the protein kinase B-mechanistic target of rapamycin (Akt-mTOR) signaling cascade. Stressors apart from exercise and nutrition,...
9.
Ducharme J, Fennel Z, McKenna Z, Nava R, Deyhle M
Am J Physiol Cell Physiol
. 2023 Jun;
325(1):C300-C313.
PMID: 37335026
Toll-like receptor 4 (TLR4) activation by lipopolysaccharides (LPS) increases proinflammatory cytokine production and upregulation of muscle atrophy signaling pathways. Muscle contractions can suppress LPS/TLR4 axis activation by reducing the protein...
10.
McKenna Z, Bellovary B, Ducharme J, Deyhle M, Wells A, Fennel Z, et al.
Eur J Sport Sci
. 2023 Apr;
23(10):2002-2010.
PMID: 37051668
Hypoxia induced intestinal barrier injury, microbial translocation, and local/systemic inflammation may contribute to high-altitude associated gastrointestinal complications or symptoms of acute mountain sickness (AMS). Therefore, we tested the hypothesis that...