Jeremy A Hirota
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Explore the profile of Jeremy A Hirota including associated specialties, affiliations and a list of published articles.
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78
Citations
1734
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Recent Articles
11.
Mekhael O, Revill S, Hayat A, Cass S, MacDonald K, Vierhout M, et al.
Immunol Cell Biol
. 2023 Mar;
101(5):412-427.
PMID: 36862017
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrotic interstitial lung disease of unknown etiology. The accumulation of macrophages is associated with disease pathogenesis. The unfolded protein response (UPR) has...
12.
Wang Y, Singer R, Liu X, Inman S, Cao Q, Zhou Q, et al.
Front Bioeng Biotechnol
. 2022 Nov;
10:959335.
PMID: 36329705
Integration of mechanical cues in conventional 2D or 3D cell culture platforms is an important consideration for and models of lung health and disease. Available commercial and published custom-made devices...
13.
Rajasekar S, Lin D, Zhang F, Sotra A, Boshart A, Clotet-Freixas S, et al.
Lab Chip
. 2022 Apr;
22(10):1929-1942.
PMID: 35383790
Organ-on-a-chip systems that recapitulate tissue-level functions have been proposed to improve - correlation in drug development. Significant progress has been made to control the cellular microenvironment with mechanical stimulation and...
14.
Carpio M, Dabaghi M, Ungureanu J, Kolb M, Hirota J, Moran-Mirabal J
Front Bioeng Biotechnol
. 2021 Dec;
9:773511.
PMID: 34900964
Human lungs are organs with an intricate hierarchical structure and complex composition; lungs also present heterogeneous mechanical properties that impose dynamic stress on different tissue components during the process of...
15.
Huff R, Hirota J
Am J Respir Cell Mol Biol
. 2021 Oct;
66(1):10-11.
PMID: 34705618
No abstract available.
16.
Dabaghi M, Tiessen N, Cao Q, Chandiramohan A, Saraei N, Kim Y, et al.
ACS Biomater Sci Eng
. 2021 Oct;
7(11):5301-5314.
PMID: 34696583
This work describes a versatile and cost-effective cell culture method for micropatterning and growing adherent cells on porous membranes using pressure-sensitive double-sided adhesives. This technique also allows cell culture using...
17.
Pablos I, Machado Y, de Jesus H, Mohamud Y, Kappelhoff R, Lindskog C, et al.
Cell Rep
. 2021 Oct;
37(4):109892.
PMID: 34672947
The main viral protease (3CL) is indispensable for SARS-CoV-2 replication. We delineate the human protein substrate landscape of 3CL by TAILS substrate-targeted N-terminomics. We identify more than 100 substrates in...
18.
Kim Y, Hou V, Huff R, Aguiar J, Revill S, Tiessen N, et al.
Respir Res
. 2021 Oct;
22(1):266.
PMID: 34666750
Introduction: Over 300 million people in the world live with asthma, resulting in 500,000 annual global deaths with future increases expected. It is estimated that around 50-80% of asthma exacerbations...
19.
Hanson P, Liu-Fei F, Minato T, Hossain A, Rai H, Chen V, et al.
Lab Invest
. 2021 Oct;
102(1):14-24.
PMID: 34608239
The prevalence and contribution of cardiotropic viruses to various expressions of heart failure are increasing, yet primarily underappreciated and underreported due to variable clinical syndromes, a lack of consensus diagnostic...
20.
Nguyen J, Huff R, Cao Q, Tiessen N, Carlsten C, Hirota J
Toxicol In Vitro
. 2021 Oct;
77:105253.
PMID: 34601066
The airway epithelium is exposed to a variety of air pollutants, which have been associated with the onset and worsening of respiratory diseases. These air pollutants can vary depending on...