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Kjetil Ask

Explore the profile of Kjetil Ask including associated specialties, affiliations and a list of published articles. Areas
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Articles 93
Citations 2687
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Recent Articles
1.
Isshiki T, Sunakawa M, Vierhout M, Ayoub A, Ali P, Naiel S, et al.
Front Med (Lausanne) . 2025 Jan; 12:1532437. PMID: 39881845
Background: Sarcoidosis is a systemic granulomatous disease of unknown cause. Natural improvement with favorable outcome is common, but a significant number of patients present with difficult to manage and progressive...
2.
He D, Shannon C, Hirota J, Ask K, Ryerson C, Tebbutt S
PLoS One . 2024 Dec; 19(12):e0314876. PMID: 39625896
Fibrotic interstitial lung diseases (ILDs) result from excessive deposition of extracellular matrix (ECM) proteins in the lung, causing irreversible damage to the lung architecture. Clinical management of ILDs differs depending...
3.
Vierhout M, Ayoub A, Ali P, Kumaran V, Naiel S, Isshiki T, et al.
Biochem Biophys Res Commun . 2024 Nov; 741:151038. PMID: 39603027
Idiopathic pulmonary fibrosis (IPF) is fatal interstitial lung disease characterized by excessive scarring of the lung tissue and declining respiratory function. Given its short prognosis and limited treatment options, novel...
4.
Pommerolle L, Beltramo G, Biziorek L, Truchi M, Dias A, Dondaine L, et al.
Thorax . 2024 Jul; 79(12):1124-1135. PMID: 39033028
Background: Interstitial lung diseases (ILDs) include a large number of diseases associated with progressive pulmonary fibrosis (PPF), including idiopathic pulmonary fibrosis (IPF). Despite the rarity of each of the fibrotic...
5.
Marrow J, Alshamali R, Edgett B, Allwood M, Cochrane K, Al-Sabbag S, et al.
Front Physiol . 2024 Jul; 15:1397049. PMID: 39011088
Erythropoietin (EPO) exerts non-canonical roles beyond erythropoiesis that are developmentally, structurally, and physiologically relevant for the heart as a paracrine factor. The role for paracrine EPO signalling and cellular crosstalk...
6.
Allwood M, Edgett B, Platt M, Marrow J, Coyle-Asbil B, Holjak E, et al.
J Mol Cell Cardiol . 2024 Feb; 188:90-104. PMID: 38382296
The role of erythropoietin (EPO) has extended beyond hematopoiesis to include cytoprotection, inotropy, and neurogenesis. Extra-renal EPO has been reported for multiple tissue/cell types, but the physiological relevance remains unknown....
7.
Isshiki T, Naiel S, Vierhout M, Otsubo K, Ali P, Tsubouchi K, et al.
Pharmacol Ther . 2023 Dec; 253:108578. PMID: 38103794
The treatment of interstitial lung diseases, including idiopathic pulmonary fibrosis (IPF), remains challenging as current available antifibrotic agents are not effective in halting disease progression. Connective tissue growth factor (CTGF),...
8.
Milad N, Fantauzzi M, McGrath J, Cass S, Thayaparan D, Wang P, et al.
ERJ Open Res . 2023 Nov; 9(6). PMID: 38020563
Rationale: Despite its increasingly widespread use, little is known about the impact of cannabis smoking on the response to viral infections like influenza A virus (IAV). Many assume that cannabis...
9.
Yanagihara T, Zhou Q, Tsubouchi K, Revill S, Ayoub A, Gholiof M, et al.
Biochem Biophys Res Commun . 2023 Mar; 656:53-62. PMID: 36958255
Type 1 alveolar epithelial cells (AT1s) and type 2 alveolar epithelial cells (AT2s) regulate the structural integrity and function of alveoli. AT1s mediate gas exchange, whereas AT2s serve multiple functions,...
10.
Isshiki T, Vierhout M, Naiel S, Ali P, Yazdanshenas P, Kumaran V, et al.
Biochem Pharmacol . 2023 Mar; 211:115501. PMID: 36921632
Idiopathic pulmonary fibrosis (IPF) is the representative phenotype of interstitial lung disease where severe scarring develops in the lung interstitium. Although antifibrotic treatments are available and have been shown to...