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Jeong-Heon Lee

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Articles 88
Citations 2636
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Recent Articles
1.
Sohn H, Ham A, Park A, Lee J, Park S, Shin H, et al.
Sci Rep . 2025 Feb; 15(1):7015. PMID: 40016342
Naegleria fowleri is a free-living amoeba found in lakes, soil, hot springs, and poorly chlorinated swimming pools. It is pathogenic to humans, causing a rare and fatal brain infection known...
2.
Wagner R, Hlady R, Pan X, Wang L, Kim S, Zhao X, et al.
Genome Biol . 2025 Feb; 26(1):22. PMID: 39910618
Background: SETD2 is the sole epigenetic factor responsible for catalyzing histone 3, lysine 36, tri-methylation (H3K36me3) in mammals. Its role in regulating cellular processes such as RNA splicing, DNA repair,...
3.
Kang H, Sohn H, Park A, Ham A, Lee J, Oh Y, et al.
Sci Rep . 2025 Jan; 15(1):3528. PMID: 39875468
No abstract available.
4.
Mohammed Ismail W, Fernandez J, Fernandez J, Binder M, Lasho T, Kim M, et al.
Blood Adv . 2024 Dec; 9(2):402-416. PMID: 39631069
DNMT3A and TET2 are epigenetic regulator genes commonly mutated in age-related clonal hematopoiesis (CH). Despite having opposed epigenetic functions, these mutations are associated with increased all-cause mortality and a low...
5.
Bhunia M, Stehn C, Jubenville T, Novacek E, Larsson A, Madala M, et al.
Neurooncol Adv . 2024 Dec; 6(1):vdae188. PMID: 39620202
Background: Malignant peripheral nerve sheath tumors (MPNSTs) can arise from atypical neurofibromas (ANF). Loss of the polycomb repressor complex 2 (PRC2) is a common event. Previous studies on PRC2-regulated genes...
6.
Rakshit K, Brown M, Javeed N, Lee J, Ordog T, Matveyenko A
iScience . 2024 Nov; 27(11):111179. PMID: 39524327
The circadian clock plays a vital role in modulating the cellular immune response. However, its role in mediating pro-inflammatory diabetogenic β cell injury remains largely unexplored. Our studies demonstrate that...
7.
Kim K, Lee J, Hong J, Park J, Lee S, Park E, et al.
J Clin Neurol . 2024 Nov; 20(6):571-579. PMID: 39505309
Background And Purpose: We delineated the association between otolithic dysfunction and blood pressure (BP) variability. Methods: We prospectively recruited 145 consecutive patients (age=71 [59-79] years, median [interquartile range]; 76 females)...
8.
Badurdeen D, Li Z, Lee J, Ma T, Bhagwate A, Latanich R, et al.
bioRxiv . 2024 May; PMID: 38766131
Obesity is an epidemic with myriad health effects, but little is understood regarding individual obese phenotypes and how they may respond to therapy. Epigenetic changes associated with obesity have been...
9.
Sohn H, Park A, Lee J, Yun K, Song K, Kim J, et al.
Parasitol Res . 2024 Apr; 123(4):192. PMID: 38652173
The pathogenic free-living amoebae, Naegleria fowleri and Acanthamoeba polyphaga, are found in freshwater, soil, and unchlorinated or minimally chlorinated swimming pools. N. fowleri and A. polyphaga are becoming problematic as...
10.
Jachim S, Zhong J, Ordog T, Lee J, Bhagwate A, Nagaraj N, et al.
Aging (Albany NY) . 2023 Oct; 15(19):9984-10009. PMID: 37819791
Cellular senescence and circadian dysregulation are biological hallmarks of aging. Whether they are coordinately regulated has not been thoroughly studied. We hypothesize that BMAL1, a pioneer transcription factor and master...