Jeong-Heon Lee
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Explore the profile of Jeong-Heon Lee including associated specialties, affiliations and a list of published articles.
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88
Citations
2636
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Recent Articles
11.
Yoon H, Lee J, Lee J, Park E, Lee S, Kim B, et al.
J Neurol
. 2023 Oct;
271(2):819-825.
PMID: 37805976
The results of video head impulse tests (video-HITs) may be confounded by data artifacts of various origins, including pupil size and eyelid obstruction of the pupil. This study aimed to...
12.
Gao F, Hayashi Y, Saravanaperumal S, Gajdos G, Syed S, Bhagwate A, et al.
Gastroenterology
. 2023 Aug;
165(6):1458-1474.
PMID: 37597632
Background & Aims: Although depletion of neuronal nitric oxide synthase (NOS1)-expressing neurons contributes to gastroparesis, stimulating nitrergic signaling is not an effective therapy. We investigated whether hypoxia-inducible factor 1α (HIF1A),...
13.
Wang T, Wagner R, Hlady R, Pan X, Zhao X, Kim S, et al.
Mol Oncol
. 2023 Jul;
18(1):44-61.
PMID: 37418588
Histone-lysine N-methyltransferase SETD2 (SETD2), the sole histone methyltransferase that catalyzes trimethylation of lysine 36 on histone H3 (H3K36me3), is often mutated in clear cell renal cell carcinoma (ccRCC). SETD2 mutation...
14.
Sandoval L, Mohammed Ismail W, Mazzone A, Dumbrava M, Fernandez J, Munankarmy A, et al.
Genes (Basel)
. 2023 Jun;
14(6).
PMID: 37372428
The snATAC + snRNA platform allows epigenomic profiling of open chromatin and gene expression with single-cell resolution. The most critical assay step is to isolate high-quality nuclei to proceed with...
15.
Caride A, Jang J, Shi G, Lenz S, Zhong J, Kim K, et al.
BMC Genomics
. 2023 Apr;
24(1):171.
PMID: 37016279
Chromatin immunoprecipitation (ChIP) is an antibody-based approach that is frequently utilized in chromatin biology and epigenetics. The challenge in experimental variability by unpredictable nature of usable input amounts from samples...
16.
Mohammed Ismail W, Mazzone A, Ghiraldini F, Kaur J, Bains M, Munankarmy A, et al.
Commun Biol
. 2023 Feb;
6(1):215.
PMID: 36823213
Considerable efforts have been made to characterize active enhancer elements, which can be annotated by accessible chromatin and H3 lysine 27 acetylation (H3K27ac). However, apart from poised enhancers that are...
17.
Nguyen T, Gao H, Liu D, Philips T, Ye Z, Lee J, et al.
Nucleic Acids Res
. 2022 Nov;
50(20):11635-11653.
PMID: 36399508
Understanding the function of non-coding genomic sequence variants represents a challenge for biomedicine. Many diseases are products of gene-by-environment interactions with complex mechanisms. This study addresses these themes by mechanistic...
18.
Thaler R, Khani F, Sturmlechner I, Dehghani S, Denbeigh J, Zhou X, et al.
Nat Commun
. 2022 Oct;
13(1):5883.
PMID: 36202795
Vitamin C deficiency disrupts the integrity of connective tissues including bone. For decades this function has been primarily attributed to Vitamin C as a cofactor for collagen maturation. Here, we...
19.
Kim S, Lee J, Baek S, Lee S, Yu S, Kim J
J Neuroophthalmol
. 2022 Sep;
43(4):e280-e282.
PMID: 36166775
No abstract available.
20.
Nguyen T, Liu D, Gao H, Ye Z, Lee J, Wei L, et al.
Clin Transl Sci
. 2022 Sep;
15(11):2758-2771.
PMID: 36128656
Alternative polyadenylation (APA) is a common genetic regulatory mechanism that generates distinct 3' ends for RNA transcripts. Changes in APA have been associated with multiple biological processes and disease phenotypes....