Jens Lykke-Andersen
Overview
Explore the profile of Jens Lykke-Andersen including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
50
Citations
4193
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Ocheltree C, Skrable B, Pimentel A, Nicholson-Shaw T, Lee S, Lykke-Andersen J
bioRxiv
. 2025 Feb;
PMID: 39975393
Small non-coding RNAs (sncRNAs) are subject to a variety of 3' end trimming and tailing activities during biogenesis, which dictate whether they undergo maturation or are instead subjected to degradation....
2.
Dowdle M, Lykke-Andersen J
Nat Rev Genet
. 2025 Jan;
PMID: 39870755
mRNA degradation pathways have key regulatory roles in gene expression. The intrinsic stability of mRNAs in the cytoplasm of eukaryotic cells varies widely in a gene- and isoform-dependent manner and...
3.
Ma T, Xiong E, Lardelli R, Lykke-Andersen J
Proc Natl Acad Sci U S A
. 2024 Jan;
121(3):e2315259121.
PMID: 38194449
Competing exonucleases that promote 3' end maturation or degradation direct quality control of small non-coding RNAs, but how these enzymes distinguish normal from aberrant RNAs is poorly understood. The Pontocerebellar...
4.
Li H, Ma T, Remsberg J, Won S, DeMeester K, Njomen E, et al.
Nat Chem Biol
. 2023 Oct;
19(11):1320-1330.
PMID: 37783940
Covalent chemistry represents an attractive strategy for expanding the ligandability of the proteome, and chemical proteomics has revealed numerous electrophile-reactive cysteines on diverse human proteins. Determining which of these covalent...
5.
Ma T, Xiong E, Lardelli R, Lykke-Andersen J
bioRxiv
. 2023 Aug;
PMID: 37645788
Competing exonucleases that promote 3' end maturation or degradation direct quality control of small non-coding RNAs, but how these enzymes distinguish normal from aberrant RNAs is poorly understood. The Pontocerebellar...
6.
Carreno A, Lykke-Andersen J
Mol Cell Biol
. 2022 Aug;
42(9):e0005522.
PMID: 35920669
The regulation of the mRNA decay activator Tristetraprolin (TTP) by the p38 mitogen-activated protein kinase (MAPK) pathway during the mammalian inflammatory response represents a paradigm for the control of mRNA...
7.
Nicholson-Shaw T, Lykke-Andersen J
RNA
. 2022 Feb;
28(5):645-656.
PMID: 35181644
Post-transcriptional trimming and tailing of RNA 3' ends play key roles in the processing and quality control of noncoding RNAs (ncRNAs). However, bioinformatic tools to examine changes in the RNA...
8.
Lardelli R, Lykke-Andersen J
Genes Dev
. 2020 Jun;
34(13-14):989-1001.
PMID: 32499401
Polymerases and exonucleases act on 3' ends of nascent RNAs to promote their maturation or degradation but how the balance between these activities is controlled to dictate the fates of...
9.
Chousal J, Cho K, Ramaiah M, Skarbrevik D, Mora-Castilla S, Stumpo D, et al.
Dev Cell
. 2018 Feb;
44(3):392-402.e7.
PMID: 29408237
Global transcriptional silencing is a highly conserved mechanism central to the oocyte-to-embryo transition. We report the unexpected discovery that global transcriptional silencing in oocytes depends on an mRNA decay activator....
10.
Lardelli R, Schaffer A, Eggens V, Zaki M, Grainger S, Sathe S, et al.
Nat Genet
. 2017 Jan;
49(3):457-464.
PMID: 28092684
Deadenylases are best known for degrading the poly(A) tail during mRNA decay. The deadenylase family has expanded throughout evolution and, in mammals, consists of 12 Mg-dependent 3'-end RNases with substrate...