Jennifer S Cavet
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Explore the profile of Jennifer S Cavet including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Jesse H, Roberts I, Cavet J
Adv Microb Physiol
. 2014 Dec;
65:83-123.
PMID: 25476765
Listeria monocytogenes is responsible for one of the most life-threatening food-borne infections and the leading cause of food-poisoning associated deaths in the UK. Infection may be of the unborn/newly born...
12.
Cavet J
Chem Biol
. 2014 Aug;
21(8):921-2.
PMID: 25126988
The innate toxicity of copper can be exploited as an antimicrobial. In this issue of Chemistry & Biology Festa and colleagues report the use of QBP, a prochelator form of...
13.
Osman D, Patterson C, Bailey K, Fisher K, Robinson N, Rigby S, et al.
Mol Microbiol
. 2012 Nov;
87(3):466-77.
PMID: 23171030
Periplasmic Cu,Zn-superoxide dismutases (Cu,Zn-SODs) are implicated in bacterial virulence. It has been proposed that some bacterial P(1B)-type ATPases supply copper to periplasmic cupro-proteins and such transporters have also been implicated...
14.
Corbett D, Wang J, Schuler S, Lopez-Castejon G, Glenn S, Brough D, et al.
Infect Immun
. 2011 Oct;
80(1):14-21.
PMID: 22025520
We report here the identification and characterization of two zinc uptake systems, ZurAM and ZinABC, in the intracellular pathogen Listeria monocytogenes. Transcription of both operons was zinc responsive and regulated...
15.
Osman D, Cavet J
Adv Microb Physiol
. 2011 Jul;
58:175-232.
PMID: 21722794
Both the essentiality and toxicity of transition metals are exploited as part of mammalian immune defenses against bacterial infection. Salmonella serovars continue to cause serious medical and veterinary problems worldwide...
16.
Corbett D, Schuler S, Glenn S, Andrew P, Cavet J, Roberts I
Mol Microbiol
. 2011 May;
81(2):457-72.
PMID: 21564342
We have characterized the csoR-copA-copZ copper resistance operon of the important human intracellular pathogen Listeria monocytogenes. Transcription of the operon is specifically induced by copper, and mutants lacking the P₁-type...
17.
Wang Y, Kendall J, Cavet J, Giedroc D
Biochemistry
. 2010 Jul;
49(31):6617-26.
PMID: 20586430
Metal homeostasis and resistance in bacteria is maintained by a panel of metal-sensing transcriptional regulators that collectively control transition metal availability and mediate resistance to heavy metal xenobiotics, including As(III),...
18.
Osman D, Waldron K, Denton H, Taylor C, Grant A, Mastroeni P, et al.
J Biol Chem
. 2010 Jun;
285(33):25259-68.
PMID: 20534583
Salmonella enterica sv. typhimurium (S. enterica sv. Typhimurium) has two metal-transporting P(1)-type ATPases whose actions largely overlap with respect to growth in elevated copper. Mutants lacking both ATPases over-accumulate copper...
19.
Osman D, Cavet J
Nat Prod Rep
. 2010 May;
27(5):668-80.
PMID: 20442958
Detecting deficiency and excess of different metal ions is fundamental for every organism. Our understanding of how metals are detected by bacteria is exceptionally well advanced, and multiple families of...
20.
Beresford N, Mulhearn D, Szczepankiewicz B, Liu G, Johnson M, Fordham-Skelton A, et al.
J Antimicrob Chemother
. 2009 Feb;
63(5):928-36.
PMID: 19240079
Objectives: The secreted Mycobacterium tuberculosis protein tyrosine phosphatase (MptpB) is a virulence factor for M. tuberculosis and contributes to its survival within host macrophages. The aim of this study was...